Name | Pentaethylene glycol |
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Synonyms |
Pentaethylene Glycol
3,6,9,12-Tetraoxatetradecane-1,14-diol,Pentaglycol MFCD00002878 EINECS 225-341-4 pentaethyleneglycol 2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethanol 3,6,9,12-Tetraoxatetradecane-1,14-diol |
Description | Pentaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 356.1±32.0 °C at 760 mmHg |
Molecular Formula | C10H22O6 |
Molecular Weight | 238.278 |
Flash Point | 169.2±25.1 °C |
Exact Mass | 238.141632 |
PSA | 77.38000 |
LogP | -2.59 |
Vapour Pressure | 0.0±1.8 mmHg at 25°C |
Index of Refraction | 1.458 |
Stability | Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides. |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xi:Irritant; |
Risk Phrases | R36/37/38 |
Safety Phrases | S26-S36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | RZ2670000 |
HS Code | 2909499000 |
HS Code | 2909499000 |
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Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |