196195-13-8

196195-13-8 structure

Name: 4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine
Chemical Name: 4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine
CAS Number: 196195-13-8
Molecular Formula: C₁₆H₂₀ClN₃O₃
Molecular Weight: 337.80100
Create Date: 2018-12-25 14:59:52
Modify Date: 2024-01-14 14:26:47

Name	4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine
Synonyms	Quinazoline,4-chloro-6-methoxy-7-[3-(4-morpholinyl)propoxy] 4-chloro-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazoline 4chloro-6-methoxy-7-(3-morpholinopropoxy)quinazoline

Molecular Formula	C₁₆H₂₀ClN₃O₃
Molecular Weight	337.80100
Exact Mass	337.11900
PSA	56.71000
LogP	2.33080

196194-62-4

~87%

196195-13-8

Literature: AstraZeneca AB Patent: EP1119567 B1, 2005 ; Location in patent: Page/Page column 27 ;

144-55-8

196194-62-4

~60%

196195-13-8

Literature: AstraZeneca AB Patent: US7235559 B1, 2007 ; US 7235559 B1

162364-72-9

179688-01-8

108-95-2

193001-55-7

Detail

Literature: Hennequin, Laurent Francois Andre; Ple, Patrick; Lambert, Christine Marie Paul Patent: US2004/34046 A1, 2004 ;

4441-30-9

196195-13-8

Literature: Ple, Patrick A.; Green, Tim P.; Hennequin, Laurent F.; Curwen, Jon; Fennell, Michael; Allen, Jack; Lambert-Van Der Brempt, Christine; Costello, Gerard Journal of Medicinal Chemistry, 2004 , vol. 47, # 4 p. 871 - 887

196195-12-7

196195-13-8

3943-74-6

196195-13-8

Literature: Cai, Jin; Sun, Min; Wu, Xiaoqing; Chen, Junqing; Wang, Peng; Zong, Xi; Ji, Min European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 702 - 712

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4