4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine

Modify Date: 2024-01-14 14:26:47

4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine Structure
4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine structure
Common Name 4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine
CAS Number 196195-13-8 Molecular Weight 337.80100
Density N/A Boiling Point N/A
Molecular Formula C16H20ClN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C16H20ClN3O3
Molecular Weight 337.80100
Exact Mass 337.11900
PSA 56.71000
LogP 2.33080

 Synthetic Route

~87%

4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine Structure

4-[3-(4-chloro-...

CAS#:196195-13-8

Literature: AstraZeneca AB Patent: EP1119567 B1, 2005 ; Location in patent: Page/Page column 27 ;

~60%

4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine Structure

4-[3-(4-chloro-...

CAS#:196195-13-8

Literature: AstraZeneca AB Patent: US7235559 B1, 2007 ; US 7235559 B1

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Detail
Literature: Hennequin, Laurent Francois Andre; Ple, Patrick; Lambert, Christine Marie Paul Patent: US2004/34046 A1, 2004 ;

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4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine Structure

4-[3-(4-chloro-...

CAS#:196195-13-8

Literature: Ple, Patrick A.; Green, Tim P.; Hennequin, Laurent F.; Curwen, Jon; Fennell, Michael; Allen, Jack; Lambert-Van Der Brempt, Christine; Costello, Gerard Journal of Medicinal Chemistry, 2004 , vol. 47, # 4 p. 871 - 887

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4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine Structure

4-[3-(4-chloro-...

CAS#:196195-13-8

Literature: Ple, Patrick A.; Green, Tim P.; Hennequin, Laurent F.; Curwen, Jon; Fennell, Michael; Allen, Jack; Lambert-Van Der Brempt, Christine; Costello, Gerard Journal of Medicinal Chemistry, 2004 , vol. 47, # 4 p. 871 - 887

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4-[3-(4-chloro-6-methoxyquinazolin-7-yl)oxypropyl]morpholine Structure

4-[3-(4-chloro-...

CAS#:196195-13-8

Literature: Cai, Jin; Sun, Min; Wu, Xiaoqing; Chen, Junqing; Wang, Peng; Zong, Xi; Ji, Min European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 702 - 712

 Synonyms

Quinazoline,4-chloro-6-methoxy-7-[3-(4-morpholinyl)propoxy]
4-chloro-6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazoline
4chloro-6-methoxy-7-(3-morpholinopropoxy)quinazoline