3943-74-6

3943-74-6 structure

Name: Methyl vanillate
Chemical Name: methyl vanillate
CAS Number: 3943-74-6
Molecular Formula: C₉H₁₀O₄
Molecular Weight: 182.173
Catalog: Chemical reagent Organic reagent Ester Methyl ester compound
Create Date: 2018-08-24 13:13:49
Modify Date: 2026-07-10 13:40:42
Methyl vanillate, one of the ingredients in Hovenia dulcis Thunb, is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.

Name	methyl vanillate
Synonyms	4-hydroxy-3-methoxy Methy Benzoate 4-Hydroxy-3-methoxybenzoic acid methyl ester (methyl vanillate) TIMTEC-BB SBB008281 VANILLIC ACID METHYL ESTER Vanillic acid, methyl ester (8CI) 4-hydroxy-3-methoxy-benzoicacimethylester 4-HYDROXY-3-METHOXYBENZOIC ACID METHYL ESTER Vanillic Acid Methyl Ester Methyl 4-Hydroxy-3-methoxybenzoate 4-Hydroxy-3-methoxybenzoic Acid Methyl Ester Methyl vanillate SynonyMs Methyl 4-hydroxy-3-Methoxybenzoate 4-Hydroxy-3-methoxybenzoic Acid Methyl Ester Benzoicacid,4-hydroxy-3-methoxy-,methylester Methylevanillate Factory Supply Hot Sale High Quality Methyl vanillate METHYL 4-HYDROXY-3-METHOXYBENZOATE Methyl vanillate, R Vanillic acid, methyl este MethylVanillate> Methyl 4-hydroxy-3-methoxybenzoate METHYL VANILLATE 4-Hydroxy-3-methoxybenzoic Acid Methyl Ester Methyl 4-Hydroxy-3-methoxybenzoate Vanillic Acid Methyl Ester RECHEM AL BF 0101 METHYL VANILLATE (CNALINE) Vanillic Acid Methyl Ester EINECS 223-525-9 Methyl ester of 4-hydroxy-3-methoxybenzoic acid Eugenol Impurity 26 MFCD00008438 3-Methoxy-4-hydroxybenzoic acid methyl ester Methyl4-hydroxy-3-mehtoxybenzoate methylvanillate,methyl4-hydroxy-3-methoxybenzoate Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester METHYL 3-METHOXY-4-HYDROXYBENZOATE Vanillic acid methyl Methyl vanillic acid

Description	Methyl vanillate, one of the ingredients in Hovenia dulcis Thunb, is a Wnt/β-catenin pathway activator[1]. A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> Wnt Natural Products >> Acids and Aldehydes Research Areas >> Inflammation/Immunology
Target	Wnt/β-catenin[1]
In Vitro	Methyl vanillate (0-100 μM) increases the expression and nuclear translocation of β-catenin in calvarial osteoblasts. Methyl vanillate dose-dependently elevates ALP activity in calvarial osteoblasts[1].
References	[1]. Cha PH, et al. Hovenia dulcis Thunb extract and its ingredient methyl vanillate activate Wnt/β-catenin pathway and increase bone mass in growing or ovariectomized mice. PLoS One. 2014 Jan 22;9(1):e85546.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#06782

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DH2430000
HS Code	2918990090

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%