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62595-14-6

62595-14-6 structure
62595-14-6 structure
  • Name: L-Tyrosine (Ring-D4)
  • Chemical Name: L-4-Hydroxyphenyl-2,3,5,6-d4-alanine
  • CAS Number: 62595-14-6
  • Molecular Formula: C9H7D4NO3
  • Molecular Weight: 185.213
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-12-22 11:41:05
  • Modify Date: 2024-01-09 20:22:25
  • L-Tyrosine D4 is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1].

Name L-4-Hydroxyphenyl-2,3,5,6-d4-alanine
Synonyms (2S)-2-amino-3-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)propanoic acid
L-(2,3,5,6-H)Tyrosine
L-4-Hydroxyphenyl-d4-alanine
L-TYROSINE-2,3,5,6-D4
L-4-Hydroxyphenyl-2,3,5,6-d4-alanine
MFCD00079605
L-Tyrosine-2,3,5,6-d
Description L-Tyrosine D4 is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1].
Related Catalog
In Vitro L-Tyrosine inhibits citrate synthase activity in the posterior cortex (2.0 and 4.0 mM), malate dehydrogenase is not altered by L-Tyrosine and succinate dehydrogenase is increased in the posterior cortex (0.1-4.0 mM), hippocampus (1.0-4.0 mM), striatum (4.0 mM) and liver (0.1-4.0 mM)[1].
References

[1]. Ferreira GK, et al. Effect of L-tyrosine in vitro and in vivo on energy metabolism parameters in brain and liver of young rats. Neurotox Res. 2013 May;23(4):327-35.

Density 1.3±0.1 g/cm3
Boiling Point 385.2±32.0 °C at 760 mmHg
Melting Point >300ºC (dec.)(lit.)
Molecular Formula C9H7D4NO3
Molecular Weight 185.213
Flash Point 186.7±25.1 °C
Exact Mass 185.098999
PSA 83.55000
LogP 0.38
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.614
Storage condition 2-8°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
Precursor  3

DownStream  1