| Name | L-4-Hydroxyphenyl-2,3,5,6-d4-alanine |
|---|---|
| Synonyms |
(2S)-2-amino-3-(2,3,5,6-tetradeuterio-4-hydroxyphenyl)propanoic acid
L-(2,3,5,6-H)Tyrosine L-4-Hydroxyphenyl-d4-alanine L-TYROSINE-2,3,5,6-D4 L-4-Hydroxyphenyl-2,3,5,6-d4-alanine MFCD00079605 L-Tyrosine-2,3,5,6-d |
| Description | L-Tyrosine D4 is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1]. |
|---|---|
| Related Catalog | |
| In Vitro | L-Tyrosine inhibits citrate synthase activity in the posterior cortex (2.0 and 4.0 mM), malate dehydrogenase is not altered by L-Tyrosine and succinate dehydrogenase is increased in the posterior cortex (0.1-4.0 mM), hippocampus (1.0-4.0 mM), striatum (4.0 mM) and liver (0.1-4.0 mM)[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 385.2±32.0 °C at 760 mmHg |
| Melting Point | >300ºC (dec.)(lit.) |
| Molecular Formula | C9H7D4NO3 |
| Molecular Weight | 185.213 |
| Flash Point | 186.7±25.1 °C |
| Exact Mass | 185.098999 |
| PSA | 83.55000 |
| LogP | 0.38 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.614 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
|
~86%
62595-14-6 |
| Literature: Nishiyama; Oba; Ueno; Morita; Nakamura; Kainosho Journal of Labelled Compounds and Radiopharmaceuticals, 1994 , vol. 34, # 9 p. 831 - 837 |
|
~%
62595-14-6 |
| Literature: Journal of Organic Chemistry, , vol. 51, # 8 p. 1175 - 1179 |
| Precursor 3 | |
|---|---|
| DownStream 1 | |