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64228-81-5

64228-81-5 structure
64228-81-5 structure
  • Name: atracurium besylate
  • Chemical Name: atracurium besylate
  • CAS Number: 64228-81-5
  • Molecular Formula: C65H82N2O18S2
  • Molecular Weight: 1243.479
  • Catalog: Chemical reagent Organic reagent Sulfonate/sulfinate
  • Create Date: 2018-07-18 17:48:06
  • Modify Date: 2026-07-03 17:38:45
  • Atracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg. Target: nAChRAtracurium besylate is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Atracurium is classified as an intermediate-duration non-depolarizing neuromuscular-blocking agent [1]. A 14C radiolabeled metabolism study in cats confirmed the lack of hepatic or renal involvement in the metabolism of atracurium: radioactivity eliminated in bile and urine was predominantly from metabolites rather than the unchanged parent drug [2].
Name atracurium besylate
Synonyms 2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-Isoquinolinium, benzenesulfonate (1:2)
(1R,2R)-1-[(3,4-diMethoxyphenyl)Methyl]-2-(3-{[5-({3-[(1R,2R)-1-[(3,4-diMethoxyphenyl)Methyl]-6,7-diMethoxy-2-Methyl-1,2,3,4-tetrahydroisoquinolin-2-iuM-2-yl]propanoyl}oxy)pentyl]oxy}-3-oxopropyl)-6,7-diMethoxy-2-Methyl-1,2,3,4-tetrahydroisoquinolin-2-iuM
Atracurium for impurity F identification CRS
NIMBEX
AtracuriumBesylate(DMF)
Atracurium besylate, a neuromusculblocking agent
AtracuriuM besylate (TracriuM)
Pentamethylen bis(3-(1,2,3,4-tetrahydro-6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-2-methyl-2-isochinolyl)propionat)bis(benzolsulfonat)
2,2'-((Pentane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium) benzenesulfonate
EINECS 264-743-4
AttracuriumBesylate
2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)meth
51W-89：Nimbex
Atracurim besylate
ATRACURIUMBESYLATE
BW-33A
Tracur
CIS-ATRACURIUM BESYLETE
atracurium besilate [INN_en]
Wellcome 33A74
2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-{[3,4-bis(methyloxy)phenyl]methyl}-2-methyl-6,7-bis(methyloxy)-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate
2，2’-[1，5-Pentanediylbis[oxy(3-oxcr3，1-propanediyl)]]bis[1-[(3，4-dimethoxyphenyl)methyl]-1，2，3，4-tetrahydro-6，7-dimethoxy-2-methylisoquinolinium]dibenzenesulfonate
2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium dibenzenesulfonate
CisatracuriumBesilete
Atracurium Dibesylate
ATRACURIUM BESYLATE /BP
2,2'-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium Benzenesulfonate
Atracurim besylate Bp
3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoic acid 5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydr
2,2'-{Pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate
ATRACURIUM BESYLAT
tracurium Besylate
Atracurium besilate CRS
Atracuricum Besilate
Bensulfuramtorisone
ATRACURIUM BESILATE INJECTION
Atracurium besilate API
BW-33A, Tracrium, 2,2μ-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium]dibenzenesulfonate
Atracurium besylate a neuromusculblocking agent
ATRICURIUM BESYLATE
TRACRIUM
Atraeurium Besylate
Atracurium Besylate (BW-33A)
Atracurium besylate,2,2′-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolinium]dibenzenesulfonate, BW-33A, Tracrium
Atracurium besylate, >=
Atracurium Besylate Cisatracurium
Atracurium besilate (Y0000424)
ATRACURIUM BESILATE
Atracurium Besylate
MFCD00797403
inflammatory,anticancer,Inhibitor,Atracurium besylate,neuromusculblockade,inhibit,nAChR,GSC cells,Nicotinic acetylcholine rectors,bronchoconstriction
2,2'-{Pentan-1,5-diylbis[oxy(3-oxopropan-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisochinolinium]bisbenzolsulfonat
Atracurium benzenesulfonate
Isoquinolinium, 2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl- benzenesulfonate (1:2)
2,2'-[1,5-PENTANEDIYLBIS[OXY(3-OXO-3,1-PROPANEDIYL)]]BIS[1-[3,4-DIMETHOXYPHENYL)METHYL]-1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-METHYLISOQUINOLINIUM]DIBENZENESULFONATE
Atraculum besylate
Isoquinolinium, 2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, dibenzenesulfonate
bisbenzènesulfonate de 2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-diméthoxybenzyl)-6,7-diméthoxy-2-méthyl-1,2,3,4-tétrahydroisoquinoléinium]
2,2'-{1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] bisbenzenesulfonate
Atracurium Besylate (mixture of isomers)
Atracurium Besylate (mixture of isomers)>
Mixture of the cis-cis, cis-trans and trans-trans isomers of 2,2\\\'-[Pentane-1,5-diylbis[oxy(3-oxopropane-1,3-diyl)]]bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] dibenzenesulfonate
Atracurium besylateQ: What is Atracurium besylate Q: What is the CAS Number of Atracurium besylate Q: What is the storage condition of Atracurium besylate Q: What e the applications of Atracurium besylate
AtracuriuM Besilete
Atracurium BesyL
Cisatracudum Besylate
51W89
Description Atracurium Besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg. Target: nAChRAtracurium besylate is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Atracurium is classified as an intermediate-duration non-depolarizing neuromuscular-blocking agent [1]. A 14C radiolabeled metabolism study in cats confirmed the lack of hepatic or renal involvement in the metabolism of atracurium: radioactivity eliminated in bile and urine was predominantly from metabolites rather than the unchanged parent drug [2].
Related Catalog
References

[1]. Fagerlund, M.J., M. Dabrowski, and L.I. Eriksson, Pharmacological characteristics of the inhibition of nondepolarizing neuromuscular blocking agents at human adult muscle nicotinic acetylcholine receptor. Anesthesiology, 2009. 110(6): p. 1244-1252.

[2]. Neill, E. and D. Chapple, Metabolic studies in the cat with atracurium: a neuromuscular blocking agent designed for non-enzymic inactivation at physiological pH. Xenobiotica, 1982. 12(3): p. 203-210.
Melting Point 85-90ºC
Molecular Formula C65H82N2O18S2
Molecular Weight 1243.479
Exact Mass 1242.500366
PSA 257.60000
LogP 11.32610
Storage condition 2-8°C
Water Solubility H2O: ~27 mg/mL
RIDADR NONH for all modes of transport
WGK Germany 3
64228-78-0 structure

64228-78-0

80-18-2 structure

80-18-2

~86%

64228-81-5 structure

64228-81-5

Literature: Stenlake; Waigh; Dewar; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 515 - 524
93-40-3 structure

93-40-3

~%

64228-81-5 structure

64228-81-5

Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524
139-76-4 structure

139-76-4

~%

64228-81-5 structure

64228-81-5

Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524
6957-27-3 structure

6957-27-3

~%

64228-81-5 structure

64228-81-5

Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524
120-20-7 structure

120-20-7

~%

64228-81-5 structure

64228-81-5

Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524
6429-04-5 structure

6429-04-5

~%

64228-81-5 structure

64228-81-5

Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524
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