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6429-04-5

6429-04-5 structure
6429-04-5 structure
  • Name: Tetrahydropapaverine hydrochloride
  • Chemical Name: Tetrahydropapaverine hydrochloride
  • CAS Number: 6429-04-5
  • Molecular Formula: C20H26ClNO4
  • Molecular Weight: 379.878
  • Catalog: Biochemical Inhibitor Metabolism Hydroxylase inhibitor
  • Create Date: 2018-06-18 15:01:22
  • Modify Date: 2026-06-30 21:58:25
  • Tetrahydropapaverine hydrochloride is one of the Tetrahydroisoquinolines. Tetrahydropapaverine hydrochloride has neurotoxic effects on dopamine neurons[1][2].
Name Tetrahydropapaverine hydrochloride
Synonyms EINECS 229-213-9
Tetrahydropapaverine hydrochloride, 10 mM in DMSO
Isoquinoline,1-[(3,4-diMethoxyphenyl)Methyl]-1,2,3,4-tetrahydro-6,7-diMethoxy-,hydrochloride (1:1)
Tetrahydropapavine Hydrochloride
Papaverine, 1,2,3,4-tetrahydro-, hydrochloride
MFCD00035267
NorlaudanosineHydrochloride>
Tetrahydropapaverine crystalline HCL
tetrahydropapaverine crystalline*hydrochloride
RS-Tetrahydropapaverine HCl (RS-THP)
1,2,3,4-Tetrahydropapaverine hydrochloride
Tetrahydropapaverine (hydrochloride) (Papaverine Impurity)
TIANFUCHEM-6-5-Tetrahydropapaverine hydrochloride in stock
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-1,2,3,4-dihydroisoquinolineHydrochloride
Norlaudanosine Hydrochloride
TETRAHYDROPAPAVERINE HCL
Nsc118072
6,7-Dimethoxy-1-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline
TETRAHYDROALKALI HYDROCHLORIDE
rac-Nor Laudanosine Hydrochloride
1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride
Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1)
1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINEHYDROCHLORIDETETRAHYDROPAPAVERINEHYDROCHLORIDE
Norlaudanosine HCl
etrahydropapaverine hydrochloride
Tetrahrdropapaverine Hydrochloride
AtracuriuM Besylate intermediate
1-[(3,4-diMethoxyphenyl)Methyl]-6,7-diMethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (1:1)
1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-Isoquinoline hydrochloride (1:1)
Papaverine Impurity E HCl (Tetrahydropapaverine HCl)
DL-NORLAUDANOSINE HYDROCHLORIDE
1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline HCl
1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDETETRAHYDROPAPAVERINE HYDROCHLORIDE
Density 1.12g/cm3
Boiling Point 475.8ºC at 760 mmHg
Melting Point 213-215ºC
Molecular Formula C20H26ClNO4
Molecular Weight 379.878
Flash Point 202.7ºC
Exact Mass 379.155029
PSA 53.53000
LogP 0.69750
Index of Refraction 1.549
Storage condition 2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NX5070700
CHEMICAL NAME :
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-veratryl-, hydrochloride
CAS REGISTRY NUMBER :
6429-04-5
LAST UPDATED :
198310
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H25-N-O4.Cl-H
MOLECULAR WEIGHT :
379.92
WISWESSER LINE NOTATION :
T66 CMT&J B1R CO1 DO1& HO1 IO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 149,200,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 149,200,1964
Hazard Codes T: Toxic;
Risk Phrases 22
Safety Phrases 36
HS Code 2939190090
6957-27-3 structure

6957-27-3

~78%

6429-04-5 structure

6429-04-5

Literature: Yamada, Koichiro; Takeda, Mikio; Iwakuma, Takeo Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 2 p. 265 - 270
13074-31-2 structure

13074-31-2

~67%

6429-04-5 structure

6429-04-5

Literature: Sladkov, V. I.; Sazonova, N. M.; Grekova, G. S.; Kalistratov, S. G.; Sokolova, A. S.; et al. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 1 p. 47 - 50 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 1 p. 50 - 53
93-40-3 structure

93-40-3

~%

6429-04-5 structure

6429-04-5

Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524
139-76-4 structure

139-76-4

~%

6429-04-5 structure

6429-04-5

Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524
120-20-7 structure

120-20-7

~%

6429-04-5 structure

6429-04-5

Literature: European Journal of Medicinal Chemistry, , vol. 16, # 6 p. 515 - 524
HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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