531-81-7

531-81-7 structure

Name: Coumarin-3-carboxylic acid
Chemical Name: Coumarin-3-carboxylic acid
CAS Number: 531-81-7
Molecular Formula: C₁₀H₆O₄
Molecular Weight: 190.15200
Catalog: Chemical reagent Organic reagent Aromatic acid
Create Date: 2018-04-21 08:00:00
Modify Date: 2026-06-30 18:08:53
Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line[1][2].

Name	Coumarin-3-carboxylic acid
Synonyms	EINECS 208-518-0 COUMIN-3-CBOXYLIC ACID Coumin-3-cboxylicacid Coumin-3-cboxylic acid, 10 mM in DMSO JR-8358, Coumin-3-cboxylic acid 2-oxochromene-3-carboxylic acid g1(rodenticide) 2-oxo-2h-1-benzopyran-3-cboxylicaci 2-oxochromene-3-cboxylic acid 2-Oxobenzopyran-3-cboxylicacid AURORA Coumin-3-cboxylic acid，(T) 2H-1-Benzopyran-3-cboxylic acid, 2-oxo 2-OXO-2H-CHROMENE-3-CBOXYLIC ACID G I(rodenticide) RECHEM AB KA K006 2-OXO-2H-1-BENZOPYRAN-3-CBOXYLIC ACID OTAVA-BB BB0125160098 Malonic acid, salicylidene-, delta-lactone Coumarin-3-Carboxylic Acid CUMINE-3-CBOXYLIC ACID 2-Oxobenzopyran-3-cboxylic acid 1-OXO-2H-BENZOPYRAN-3-CBOXYLIC ACID 3-Cboxy-2-oxo-2H-chromene, 3-Cboxycoumin, 3-Cboxy-2-oxo-2H-1-benzopyran 3-Cboxycoumin Coumin Cboxylic Acid CouMin-3-cboxylic acid, R CUMIN-3-CBOXYLIC ACID MFCD00006852

Description	Coumarin-3-carboxylic acid (2- Oxochromene-3-carboxylic acid) is an important initial compound for the synthesis of coumarins which are well known natural products for their diverse biological activities. Lanthanide complexes of Coumarin-3-carboxylic acid exhibit antiproliferative activity towards K-562 cell line[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Aimin Song, et al. A convenient synthesis of coumarin-3-carboxylic acids via Knoevenagel condensation of Meldrum's acid with ortho-hydroxyaryl aldehydes or ketones. Tetrahedron Letters. 2003 Feb;44(9): 1755-1758. [2]. Kostova I, et al. New Samarium(III), Gadolinium(III), and Dysprosium(III) Complexes of Coumarin-3-Carboxylic Acid as Antiproliferative Agents. Met Based Drugs. 2007;2007:15925.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02594

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%