110480-13-2

110480-13-2 structure

Name: EM574
Chemical Name: Ddz-L-phenylalanine
CAS Number: 110480-13-2
Molecular Formula: C₃₉H₆₉NO₁₂
Molecular Weight: 743.96
Catalog: Signaling Pathways GPCR/G Protein Motilin Receptor
Create Date: 2017-11-12 13:31:49
Modify Date: 2026-07-09 15:05:44
EM574 is a potent motilin receptor agonist in the human gastric antrum and rabbit gastrointestinal tract in vitro. EM574 is an erythromycin derivative[1].

Name	Ddz-L-phenylalanine
Synonyms	3''-N-Isopropyl-3''-N-demethyl-6-deoxy-9-deoxo-8,9-didehydro-6,9-oxyerythromycin EM574 [Motilide] Erythromycin, 8,9-didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-oxy-N-(1-methylethyl) (2S)-2-[({[2-(3,5-dimethoxyphenyl)propan-2-yl]oxy}carbonyl)amino]-3-phenylpropanoic acid de(N-methyl)-N-isopropyl-8,9-anhydroerythromycin A 6,9-hemiacetal 8,9-Didehydro-N-demethyl-9-deoxo-6-deoxy-6,9-oxy-N-(1-methylethyl)-erythromycin 6β,9-oxy-8,9-didehydro-9-deoxo-6-deoxy-3''-des(dimethylamino)-3''-(N-isopropyl-N-methylamino)erythromycin Ddz-L-Phe-OH Idremcinal EM574 (Idremcinal) Ddz-Phe-OH

Description	EM574 is a potent motilin receptor agonist in the human gastric antrum and rabbit gastrointestinal tract in vitro. EM574 is an erythromycin derivative[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Motilin Receptor
References	[1]. Guanfa Gan, et al. Intestinal absorption and presystemic elimination of the prokinetic agent, EM574, in the rabbit. J Pharm Sci. 2002 Jan;91(1):217-28.