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24782-64-7

24782-64-7 structure
24782-64-7 structure
  • Name: 4-CARBOXY-9-ACRIDANONE
  • Chemical Name: 9-oxo-10H-acridine-4-carboxylic acid
  • CAS Number: 24782-64-7
  • Molecular Formula: C14H9NO3
  • Molecular Weight: 239.22600
  • Catalog: Research Areas Others
  • Create Date: 2018-09-29 06:13:31
  • Modify Date: 2024-01-15 18:51:40
  • Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM[1].

Name 9-oxo-10H-acridine-4-carboxylic acid
Synonyms 9-oxo-9,10-dihydro-acridine-4-carboxylic acid
MFCD00957937
9,10-dihydro-9-oxoacridine-4-carboxylic acid
9,10-dihydro-9-oxo-4-acridinecarboxylic acid
4-Carboxyacridone
10H-acridin-9-one-4-carboxylic acid
4-Carboxy-9-acridanone
Description Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM[1].
Related Catalog
References

[1]. Pal C, et al. Synthesis of novel heme-interacting acridone derivatives to prevent free heme-mediated protein oxidation and degradation. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3563-7.

Density 1.397g/cm3
Boiling Point 469.9ºC at 760 mmHg
Melting Point >185 °C(dec.)
Molecular Formula C14H9NO3
Molecular Weight 239.22600
Flash Point 238ºC
Exact Mass 239.05800
PSA 70.16000
LogP 2.37950
Vapour Pressure 1.24E-09mmHg at 25°C
Index of Refraction 1.673
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
HS Code 2933990090
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%