4-CARBOXY-9-ACRIDANONE

Modify Date: 2024-01-15 18:51:40

4-CARBOXY-9-ACRIDANONE Structure
4-CARBOXY-9-ACRIDANONE structure
Common Name 4-CARBOXY-9-ACRIDANONE
CAS Number 24782-64-7 Molecular Weight 239.22600
Density 1.397g/cm3 Boiling Point 469.9ºC at 760 mmHg
Molecular Formula C14H9NO3 Melting Point >185 °C(dec.)
MSDS N/A Flash Point 238ºC

 Use of 4-CARBOXY-9-ACRIDANONE


Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM[1].

 Names

Name 9-oxo-10H-acridine-4-carboxylic acid
Synonym More Synonyms

 4-CARBOXY-9-ACRIDANONE Biological Activity

Description Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM[1].
Related Catalog
References

[1]. Pal C, et al. Synthesis of novel heme-interacting acridone derivatives to prevent free heme-mediated protein oxidation and degradation. Bioorg Med Chem Lett. 2011 Jun 15;21(12):3563-7.

 Chemical & Physical Properties

Density 1.397g/cm3
Boiling Point 469.9ºC at 760 mmHg
Melting Point >185 °C(dec.)
Molecular Formula C14H9NO3
Molecular Weight 239.22600
Flash Point 238ºC
Exact Mass 239.05800
PSA 70.16000
LogP 2.37950
Vapour Pressure 1.24E-09mmHg at 25°C
Index of Refraction 1.673

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

9-oxo-9,10-dihydro-acridine-4-carboxylic acid
MFCD00957937
9,10-dihydro-9-oxoacridine-4-carboxylic acid
9,10-dihydro-9-oxo-4-acridinecarboxylic acid
4-Carboxyacridone
10H-acridin-9-one-4-carboxylic acid
4-Carboxy-9-acridanone