Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4,4'-Diphenylmethane diisocyanate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Diphenylmethane-4,4\'-diisocyanate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

101-68-8

101-68-8 structure

Name: 4,4'-Diphenylmethane diisocyanate
Chemical Name: diphenylmethane-4,4'-diisocyanate
CAS Number: 101-68-8
Molecular Formula: C₁₅H₁₀N₂O₂
Molecular Weight: 250.252
Catalog: Organic raw materials Carboxylic compounds and derivatives Carboxylic esters and their derivatives
Create Date: 2018-12-21 09:58:41
Modify Date: 2026-06-29 22:48:04

Name	diphenylmethane-4,4'-diisocyanate
Synonyms	4,4′-Methylenebis(phenyl isocyanate),4,4′-MDI, Bis(4-isocyanatophenyl)methane METHYLENEDIPHENYLDIIOSCYANATE 4,4'-Diisocyanatodiphenylmethane, MDI 4,4′-Methylenebis(phenyl isocyanate) MFCD00036131 1,1-Methylenebis4-Isoc 4,4''-METHYLENEBIS(PHENYL ISOCYANATE) , WITH 450PPM BHT AND 450PPM TRIPHENYL PHOSPHITE Methylenebis(1,4-phenylene) diisocyanate desmodur44 METHLENEDIPHENYLISOCYANATE Diphenyl methene-4，4′diisocyanate MDI METHYLENEDIPHENYLISOCYANATE methylene 4,4'-diphenyl diisocyanate 1,1'-Methylenebis(4-isocyanatobenzene) METHYLENEBI-(PHENYLDI-ISOCYANATE) Methylene di-p-phenyl diisocyanate,flakes METHYLENEDI-P-PHENYL DIISOCYANATE Methylene di-p-phenyl diisocyanate, flakes, R 4,4'-Methylenebis(phenyl isocyanate) stab. with 450ppm BHT and 450ppm triphenyl phosphite 4,4-Diphenylmethane Diisocyanate METHYLENEBIS(P-PHENYL ISOCYANATE) bis(4-isocyanatophenyl)methane 1,1'-methanediylbis(4-isocyanatobenzene) DESMODUR Methylenediphenyl 4,4'-Diisocyanate DIPHENYLMETHAN-4,4'-DIISOCYANATE VANCHEM HM-4346 Methylenebis(1,4-phenylene)diisocyanate 1,1’-methylenebis(4-isocyanatobenzene) P,P'-DIPHENYLMETHANE DIISOCYANATE 1,1’-methylenebis(4-isocyanato-benzen 4,4'-methylene bisphenyl diisocyanate BIS(4-ISOCYANATOPHENYL)METHANE DIPHENYLMETHANEISOCYANATE EINECS 202-966-0 4,4'-Methylenediphenyl diisocyanate METHYLENE DI-P-PHENYLENE DIISOCYANATE 4,4'-Methylenebis(phenyl isocyanate) 4,4′-Methylenebis(phenyl isocyanate) Bis(4-isocyanatophenyl)methane 4,4'-DiphenyL 4,4'-METHYLENEBIS(PHENYL ISOCYANATE) caradate30 Methylene di-p-phenyl diisocyante pa,pa’-diphenylmethanediisocyanate hylenem50 Bis(4-isocyanatophenyl)methane 4,4'-Methylenebis(phenyl Isocyanate) 4,4'-Diphenylmethane Diisocyanate Methylene di-p-phenyl diisocyanate, flakes (polymerizes easily) p,p'-diphenylmethane diisocyanate Methylene di-p-phenyl diisocyanate, flakes 4,4'-Diisocyanatodiphenylmethane 4,4-Diisocyanodiphenylmethane Methylene diphenyl diisocyanate Methylene di-p-phenyl diisocyanate flakes 4,4′-MDI,4,4′-MDI, 4,4′-Methylenebis(phenyl isocyanate), Bis(4-isocyanatophenyl)methane pa,pa’-methylenebis(phenylisocyanate) 1,1'-Methanediylbis(4-isocyanatobenzene) DIPHENYLMETHANE DIISOCYANATE PMDI Methylene di-p-phenylene diisocyanate [-8] 4,4'-diphenylmethanediisocyanate METHYLENEDIPHENOLDIISOCYANATE rubinate44 Rubinate LF-168 Rubinate 44 4,4'-MDI METHYLENEDIPHENYLENE DIISOCYANATE METHYLENEDIPHENYL 4,4'-DIISOCYANATE VANCHEM HM-50 Diphenylmethandiisocyanat Isonate DIPHENYLMETHANE-4,4'-DIISOCYANATE 1,1’-methylenebis(4-isocyanato)-benzene IMO Pollution Category METHYLENEBISPHENYLDIISOCYANATE 4,4'-Methylenediphenyl isocyanate methylene

Density	1.19
Boiling Point	392 ºC
Melting Point	38-44 °C
Molecular Formula	C₁₅H₁₀N₂O₂
Molecular Weight	250.252
Flash Point	196 ºC
Exact Mass	250.074234
PSA	58.86000
LogP	4.93
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.588
Stability	Stable. Combustible. Incompatible with strong oxidizing agents. Reacts violently with alcohols.
Water Solubility	decomposes
Freezing Point	37℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NQ9350000

CHEMICAL NAME :: Isocyanic acid, methylenedi-p-phenylene ester

CAS REGISTRY NUMBER :: 101-68-8

BEILSTEIN REFERENCE NO. :: 0797662

LAST UPDATED :: 199806

DATA ITEMS CITED :: 46

MOLECULAR FORMULA :: C15-H10-N2-O2

MOLECULAR WEIGHT :: 250.27

WISWESSER LINE NOTATION :: OCNR D1R DNCO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 130 ppb/30M

TOXIC EFFECTS :: Immunological Including Allergic - increased immune response Nutritional and Gross Metabolic - body temperature increase

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 178 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 mg/m3/18H/90D-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - other changes Blood - other changes

TYPE OF TEST :: DNA damage

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

REFERENCE :: TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 36,37,1987 *** REVIEWS *** ACGIH TLV-TWA 0.051 mg/m3 (0.005 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 19,303,1979 IARC Cancer Review:Animal No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 19,303,1979 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD:air-CL 0.02 ppm (0.2 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,170,1971 OSHA PEL (Gen Indu):CL 0.02 ppm (0.2 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):CL 0.02 ppm (0.2 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):CL 0.02 ppm (0.2 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):CL 0.02 ppm (0.2 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-BELGIUM:TWA 0.005 ppm (0.051 mg/m3);STEL 0.02 ppm JAN 1993 OEL-DENMARK:TWA 0.005 ppm (0.050 mg/m3) JAN 1993 OEL-FRANCE:TWA 0.01 ppm (0.1 mg/m3);STEL 0.02 ppm (0.2 mg/m3) JAN 1993 OEL-GERMANY:TWA 0.01 ppm (0.1 mg/m3) JAN 1993 OEL-HUNGARY:TWA 0.05 mg/m3;STEL 0.1 mg/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.02 ppm (0.2 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 0.02 ppm (0.2 mg/m3) JAN 1993 OEL-POLAND:TWA 0.05 mg/m3 JAN 1993 OEL-RUSSIA:STEL 0.5 mg/m3;Skin JAN 1993 OEL-SWEDEN:TWA 0.005 ppm (0.05 mg/m3);STEL 0.01 ppm (0.1 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.01 ppm (0.1 mg/m3);STEL 0.02 ppm JAN 1993 OEL-THAILAND:TWA 0.02 ppm (0.2 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 0.02 mg/m3;STEL 0.07 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MDI-air:10H TWA 0.005 ppm;CL 0.02 ppm/10M REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 27780 No. of Facilities: 2896 (estimated) No. of Industries: 41 No. of Occupations: 48 No. of Employees: 53321 (estimated) No. of Female Employees: 13421 (estimated)

Symbol	GHS07, GHS08
Signal Word	Danger
Hazard Statements	H315-H317-H319-H332-H334-H335-H351-H373
Precautionary Statements	P261-P280-P284-P304 + P340 + P312-P305 + P351 + P338-P342 + P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R20;R36/37/38;R42/43
Safety Phrases	S23;S36/37;S45
RIDADR	UN 2811
RTECS	NQ9350000
Packaging Group	II
Hazard Class	6.1
HS Code	29291090

Precursor 5
7450-63-7 75-44-5 101-77-9 101-65-5
1266555-77-4
DownStream 10
101-65-5 22053-22-1 78-40-0 85095-61-0
7417-99-4 10097-16-2 101-77-9 7450-63-7
86672-45-9 58890-25-8

HS Code	2929109000
Summary	2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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