152246-40-7

152246-40-7 structure

Name: Myristoyl-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
Chemical Name: myristoyl-arg-lys-arg-thr-leu-arg-arg-leu-oh
CAS Number: 152246-40-7
Molecular Formula: C₆₀H₁₁₇N₂₁O₁₁
Molecular Weight: 1308.71000
Catalog: Signaling Pathways Epigenetics PKC
Create Date: 2016-09-06 10:27:10
Modify Date: 2024-01-10 18:33:06
N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM.? histone phosphorylation with IC50 of 80 μM[1][2].

Name	myristoyl-arg-lys-arg-thr-leu-arg-arg-leu-oh
Synonyms	n-m-rkrtlrrl myr-n-rkrtlrrl-oh n-myr-arg-lys-arg-thr-leu-arg-arg-leu myristoyl-arg-lys-arg-thr-leu-arg-arg-leu myr-arg-lys-arg-thr-leu-arg-arg-leu-oh egf-r fragment 651-658,myristoylated

Description	N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM.? histone phosphorylation with IC50 of 80 μM[1][2].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Signaling Pathways >> TGF-beta/Smad >> PKC
References	[1]. David K Crockett, et al. Identification of proteins from formalin-fixed paraffin-embedded cells by LC-MS/MS. Lab Invest. 2005 Nov;85(11):1405-15. [2]. C A O'Brian, et al. A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to Adriamycin. Invest New Drugs. 1991 May;9(2):169-79.