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37839-81-9

37839-81-9 structure
37839-81-9 structure
  • Name: camp sodium salt
  • Chemical Name: 3',5'-cAMP Na Hydrate
  • CAS Number: 37839-81-9
  • Molecular Formula: C10H11N5NaO6P
  • Molecular Weight: 351.19
  • Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
  • Create Date: 2018-07-19 17:57:43
  • Modify Date: 2026-07-17 16:27:11
  • Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes[1][2][3].
Name 3',5'-cAMP Na Hydrate
Synonyms ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
3',5'-Cyclic AMP Sodium Salt Hydrate
Cyclic 3',5'-adenosine monophosphate monosodium salt
3',5'-CYCLIC AMP SODIUM SALT
Adenosine 3’,5‘-cyclic monophosphate sodium salt monohydrate
ADENOSINE-3',5'-MONOPHOSPHORIC ACID SODIUM SALT
CAMP SODIUM SALT
Cyclic 3',5'-Adenosine Monophosphate MonosodiuM
3’,5‘-Cyclic AMP sodium salt
ADENOSINE 3':5'-CYCLIC MONOPHOSPHATESODI UM
Adenosine 3',5'-Cyclic Monophosphate Sodium Salt Hydrate
CYCLIC AMP SODIUM SALT
ADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
Adenosine 3',5'-phosphoric acid sodium salt
Adenosine 3′,5′-cyclic monophosphate sodium salt, monohydrate, (HPLC)
cyclic3’,5’-(hydrogenphosphate)-adenosinmonosodiumsalt
Adenosine 3',5'-cyclic monophosphate sodium salt //BP
ADENOSINE-3'',5''-CYCLIC-MONOPHOSPHATE, SODIUM SALT, CRYSTALLINE, APPROX
ADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM
ADENOSINE-3',5'-CYCLIC PHOSPHATE SODIUM
Adenosine 3',5'-(phosphoric acid sodium) salt
Adenosine-3',5'-cyclic monophosphate monosodium salt
3μ,5μ-Cyclic AMP sodium salt, cAMP-Na
adenosine-3’,5’-cyclicmonophosphate(camp),sodiumsalt
cyclic3’,5’-ampsodiumsalt
Adenosine Cyclic 3',5'-(Hydrogen Phosphate) MonosodiuM Salt
AMP salt
Adenosine-3'
CAMP NA
Butyl cyclic adenosine monophosphate impurity 2
3’,5’-ampsodiumsalt
Adenosine 3',5'-cyclic monophosphate sodium salt
Adenosine-2' 13C
Adenosine 3'-5'-cyclic monophosphate sodium salt(cAMP-Na)
Adenosine-13C5 cyclic monophosphate sodium salt
CAMP.NA (ADENOSINE-3'',5''-CYCLIC MONOPHOSPHATE SODIUM SALT)
(4,6R,7R,7aS)
Sodium (4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide
3',5'-CYCLIC AMP Na
CYCLIC AMP NA
adenosine 3',5'-cyclic monophosphate sodium salt monohydrate
Adenosine3',5'-CyclicMonophosphateSodiumSaltHydrate>
Succinyl Cyclic Adenosine Impurity 2
Adenosine 3',5'-cyclic monophosphate sodium salt monohydrate
3:5-CAMP, NA
3',5'-Cyclic AMP Sodium Salt 3',5'-cAMP Na
cyclic3’,5’-(hydrogenphosphate)adenosinemonosodiumsalt
ADENOSINE 3'', 5''-CYCLIC MONOPHOSPHATE SODIUM SALT (CAMP-NA)
Adenosine 3μ,5μ-cyclic monophosphate monohydrate sodium salt
(4,6R,7R,7aS)-6-(6-Amino-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide, sodiuM salt
adenosine 3',5'-phosphoric acid sodium
Adenosine-3'',5''-cyclic monophosphoric acid monosodium salt
Cyclic Adenosine-3',5'-Mconophosphate sodium
4H-Furo[3,2-d]-1,3,2-dioxaphosphorin-7-ol, 6-(6-amino-9H-purin-9-yl)tetrahydro-2-hydroxy-, 2-oxide, sodium salt, (4aR,6R,7R,7aS)- (1:1)
Succinyl cyclic adenosine Phosphate impurity 2
ADENOSINE-3'.5'-CYCLIC MONOPHOSPGATE SODIUN SALT (CAMP-NA
2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide, sodium salt
Cyclo-AMPNa
A-3:5-MP, SODIUM SALT
6-(6-Amino-9H-purin-9-yl)
cyclicampsodium
Adenosine, cyclic3',5'-(hydrogen phosphate), monosodium salt (9CI)
MFCD00069736
Description Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes[1][2][3].
Related Catalog
Target

Human Endogenous Metabolite

Microbial Metabolite

In Vitro Cyclic AMP (Cyclic adenosine monophosphate) sodium modulates mediator generation. Cyclic AMP sodium suppresses the expression of pro-inflammatory cytokines, including TNF-α and IL-12, and enhances the production of the anti-inflammatory cytokine IL-10.
References

[1]. G M Fimia, et al. Cyclic AMP signaling. J Cell Sci. 2001 Jun;114(Pt 11):1971-2.  

[2]. Paolo Sassone-Corsi, et al. The cyclic AMP pathway. Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a011148.  

[3]. Aronoff DM, et, al. Short communication: differences between macrophages and dendritic cells in the cyclic AMP-dependent regulation of lipopolysaccharide-induced cytokine and chemokine synthesis. J Interferon Cytokine Res. 2006 Nov;26(11):827-33.  

Boiling Point 701.5ºC at 760 mmHg
Melting Point 219 - 220ºC
Molecular Formula C10H11N5NaO6P
Molecular Weight 351.19
Flash Point 378ºC
Exact Mass 351.034454
PSA 167.48000
LogP 0.20200
Storage condition −20°C
Water Solubility H2O: 50 mg/mL | Soluble in water (50 mg/ml).

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU7357900
CHEMICAL NAME :
Adenosine, cyclic 3',5'-(hydrogen phosphate)-, monosodium salt
CAS REGISTRY NUMBER :
37839-81-9
LAST UPDATED :
199409
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H11-N5-O6-P.Na

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
14300 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Gastrointestinal - other changes
REFERENCE :
JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 1(2),15,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
395 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor Behavioral - ataxia
REFERENCE :
JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 1(2),15,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
645 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor Behavioral - ataxia
REFERENCE :
JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976- Volume(issue)/page/year: 1(2),15,1976
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS AU7357900
HS Code 29349990
Precursor  0

DownStream  1

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