Name | azure B |
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Synonyms |
Trimethylthionine chloride
N,N-Dimethyl-7-(methylamino)-3H-phenothiazin-3-iminium chloride Methyleneazure 3-Methylamino-7-dimethylaminophenazathonium Chloride N,N,N'-Trimethylthionin EINECS 208-511-2 3-(Dimethylamino)-7-(methylamino)phenothiazin-5-ium chloride Methanaminium, N-methyl-N-[7-(methylamino)-3H-phenothiazin-3-ylidene]-, chloride (1:1) Trimethyldiaminophenazathonium Chloride Azure B eosinate Azure B,Certified Azure I Phenothiazinium, 3-(dimethylamino)-7-(methylamino)-, chloride (1:1) Phenothiazin-5-ium, 3- (dimethylamino)-7-(methylamino)-, chloride MFCD00011935 AZUR I dimethyl-[7-(methylamino)phenothiazin-3-ylidene]azanium,chloride Azure B |
Description | Azure B is a cationic dye and the major metabolite of Methylene blue. Azure B is used in making Azure eosin stains for blood smear staining. Azure B is a high-potency, selective and reversible inhibitor of monoamine oxidases (MAO)-A, with IC50s of 11 and 968 nM for recombinant human MAO-A and MAO-B, respectively. Azure B possesses significant antidepressant-like effects[1][2]. |
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Related Catalog | |
In Vivo | Azure B (4-30 mg/kg; i.p.; once) decreases immobility in the forced swim test (FST)[1]. |
References |
Melting Point | 205-210 °C (dec.)(lit.) |
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Molecular Formula | C15H16ClN3S |
Molecular Weight | 305.826 |
Exact Mass | 305.075348 |
PSA | 56.17000 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | SO5550000 |
HS Code | 2934300000 |
~% 531-55-5 |
Literature: Materials Research Bulletin, , vol. 49, # 1 p. 544 - 551 |
~% 531-55-5 |
Literature: Chemische Berichte, , vol. 39, p. 1408 Chemische Berichte, , vol. 39, p. 1808 Justus Liebigs Annalen der Chemie, , vol. 230, p. 169,170 Chemische Berichte, , vol. 39, p. 1808 |
~% 531-55-5 |
Literature: Justus Liebigs Annalen der Chemie, , vol. 230, p. 169,170 Chemische Berichte, , vol. 39, p. 1808 |
~% 531-55-5 |
Literature: Chemische Berichte, , vol. 63, p. 1341,1346 |
Precursor 3 | |
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DownStream 0 |
HS Code | 2934300000 |
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Summary | 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |