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61-73-4

61-73-4 structure
61-73-4 structure
  • Name: Methylene Blue
  • Chemical Name: methylene blue
  • CAS Number: 61-73-4
  • Molecular Formula: C16H18ClN3S
  • Molecular Weight: 319.85200
  • Catalog: Dyes and pigments dye Basic dye
  • Create Date: 2018-08-27 15:44:52
  • Modify Date: 2026-07-04 08:26:34
  • Methylene blue(Basic Blue 9) is used as a dye in chromoendoscopy, and is sprayed onto the mucosa of the gastrointestinal tract in order to identify dysplasia, or pre-cancerous lesions.

Name methylene blue
Synonyms METHYLENE BLUE STAIN
evans blue tetrasodium salt
Basovict Methylene Blue
METHYLENE BLUE, LOEFFLER
Evan's Blue
METHYLENE BLUE, ZINC-FREE
METHYLENE BLUE, CHLORIDE
METHYLENE BLUE ACCORDING TO EHRLICH
BASIC BLUE 9
Duasyn Basic Blue IAD01
METHYLENE BLUE-ALPHA
METHYLENE BLUE INDICATOR
Methylene Blue,certified
abcolmethyleneblue2bznfree
Loefflers alkaline methylene blue stain solution, Methylene Blue - potassium hydroxide solution
METHYLTHIONINI CHLORIDUM
METHYLENE BLUE CONCENTRATE ACC. TO EHR-L ICH, F. MICROSCOPY
LOEFFLER'S METHYLENE BLUE
METHYLENE BLUE WATER AND ALCOHOL SOLUBLE
MFCD00012111
CI Direct Blue 53
Chromosmon
CBLUENO.1
Methylene blue, cbol solution, for microscopy
METHYLENE BLUE
3,7-Bis(dimethylamino)-5-phenothiazinium Chloride Basic Blue 9
METHYLENE BLUE POLYCRHOME (MCFADYEN'S)
Methylene Blue 2B, Basic blue 9
3,7-BIS(DIMETHYLAMINO)PHENAZATHIONIUM CHLORIDE
Leather blue hb
METHYLENE BLUE, CHLORIDE, KOCH
Methylene Blue Chloride (Certifiable Stain)
METHYLTHIONINE CHLORIDE
METHYLENE BLUE SOLUTION ACCORDING TO LOEFFLER
Methylene Blue, certified, pureR
METHYLENE BLUE 0.05 WT. % SOLUTION &
Basic Blue 9,METHYLENE BLUE BB
METHYLENE BLUE ZF
METHYLENE BLUE, LOEFFLER FORMULA
Methylene Blue p.a
METHYLENE BLUE ALKALINE LOEFFLER
METHYLENE BLUE ACCORDING TO LOFFLER
CI BASIC BLUE 9
Ehrlichs III, Loefflers Methylene Blue
METHYLENE BLUE CONCENTRATED, WATERY,ACCO RDING, TO EHRLICH FOR MICROSCOPY
METHYLENE BLUE STAIN SOLUTION, LOEFFLER'S
Methylene blue, C.I. 52015, extra
Hidaco methylene blue salt free
abcolmethyleneblue2b
SWISS BLUE
3,7-BIS(DIMETHYLAMINO)-5-PHENOTHIAZINIUM CHLORIDE
Methylene Blue solution alkaline according to Loeffler
Methylene Blue FZ
METHYLENE BLUE, LOEFFER FORMULA
EINECS 200-515-2
MethylthioniniuM chloride
METHYLENE BLUE LOEFFLER'S
METHYLENE BLUE 2B
Methylene blue, C.I. 52015, for microscopy
METHYLENE BLUE, 0.05 WT. % SOLUTION IN W ATER
Dycosbasic Methylene Blue BB
Conbasic Blue N
Ravi Methylene Blue Z.F
METHYLENE BLUE BX
MethyleneBlueGr
METHYLENE BLUE POWDER
Description Methylene blue(Basic Blue 9) is used as a dye in chromoendoscopy, and is sprayed onto the mucosa of the gastrointestinal tract in order to identify dysplasia, or pre-cancerous lesions.
Related Catalog
References

[1]. Methylene blue, From Wikipedia

Density 1.0 g/mL at 20 °C
Melting Point 190 °C (dec.)(lit.)
Molecular Formula C16H18ClN3S
Molecular Weight 319.85200
Flash Point 45 °C
Exact Mass 319.09100
PSA 47.38000
Water Solubility 40 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SO5600000
CHEMICAL NAME :
3H-Phenothiazine, 7-(dimethylamino)-3-(methylimino)-, 3-methochloride
CAS REGISTRY NUMBER :
61-73-4
LAST UPDATED :
199710
DATA ITEMS CITED :
36
MOLECULAR FORMULA :
C16-H18-N3-S.Cl
MOLECULAR WEIGHT :
319.88
WISWESSER LINE NOTATION :
T C666 BS EY INJ EUK1&1 MN1&1 &G &421

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Human - infant
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - cyanosis Blood - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
190 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
77 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
41 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
42300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2500 mg/kg
SEX/DURATION :
female 1-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
1830 nmol/L
REFERENCE :
BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 12,1099,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1469 No. of Facilities: 4471 (estimated) No. of Industries: 35 No. of Occupations: 34 No. of Employees: 25916 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T1406 No. of Facilities: 150 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 664 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1469 No. of Facilities: 5956 (estimated) No. of Industries: 29 No. of Occupations: 51 No. of Employees: 74208 (estimated) No. of Female Employees: 43305 (estimated)
Symbol GHS02
GHS02
Signal Word Warning
Hazard Statements H226
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22;R41
Safety Phrases 26-39-36
RIDADR UN 1993 3/PG 3
WGK Germany 3
RTECS SP5740000
HS Code 2934300000
HS Code 2934300000
Summary 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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