5985-38-6

5985-38-6 structure

5985-38-6 structure

Name: l-3-hydroxy-n-methylmorphinan dihydrate
Chemical Name: l-3-hydroxy-n-methylmorphinan dihydrate
CAS Number: 5985-38-6
Molecular Formula: C₂₁H₃₃NO₉
Molecular Weight: 443.48800
Create Date: 2016-04-08 11:18:26
Modify Date: 2024-01-09 09:32:26

Name	l-3-hydroxy-n-methylmorphinan dihydrate
Synonyms	LEVORPHANOL TARTRATE SALT LEVORPHANOL TARTRATE levorphanol tartrate dihydrate LEVORPHANOLTARTRATE,USP levorphanol tartrate methanol solution L-3-HYDROXY-N-METHYLMORPHINAN

Boiling Point	410.4ºC at 760 mmHg
Molecular Formula	C₂₁H₃₃NO₉
Molecular Weight	443.48800
Flash Point	11ºC
Exact Mass	443.21600
PSA	156.99000
LogP	0.76710

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QD1924200

CAS REGISTRY NUMBER :: 5985-38-6

LAST UPDATED :: 199012

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C17-H23-N-O.C4-H6-O6.2H2-O

MOLECULAR WEIGHT :: 443.55

WISWESSER LINE NOTATION :: T6 G665/FP 2AF P FX ONT&TTJ IQ O1 &QVYQYQVQ &QH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 85,387,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 85,387,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 23 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 85,387,1951

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301-H312 + H332-H317-H334-H360
Precautionary Statements	Missing Phrase - N15.00950417-P201-P261-P280-P284-P308 + P313
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T,F
Risk Phrases	R61
Safety Phrases	53-22-36/37-45-16-7
RIDADR	UN 1544 6.1/PG 3
RTECS	QD1924200

125-72-4 structure

125-72-4

~%

5985-38-6 structure

5985-38-6

Literature: MALLINCKRODT INC. Patent: WO2006/23669 A2, 2006 ; Location in patent: Page/Page column 5-8 ;

Precursor 1
125-72-4
DownStream 0