1319-77-3

EMERGENCY OVERVIEW
Causes burns. Toxic in contact with skin and if swallowed.Toxic.Corrosive.
Potential Health Effects
Eye:
Causes eye burns. May result in corneal injury.
Skin:
Harmful if absorbed through the skin. Causes skin burns. Prolonged and/or repeated contact may cause irritation and/or dermatitis.
Ingestion:
Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. Causes gastrointestinal tract burns.
Inhalation:
May cause respiratory tract irritation.
Chronic:
Not available.

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Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Not available.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Substance is nonflammable.
Extinguishing Media:
Substance is nonflammable; use agent most appropriate to extinguish surrounding fire.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Wash area with soap and water.
Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use with adequate ventilation.
Storage:
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 1319-77-3: United States OSHA: 5 ppm TWA; 22 mg/m3 TWA Belgium - TWA: 5 ppm VLE; 22 mg/m3 VLE France - VME: 5 ppm VME; 22 mg/m3 VME Germany: 5 ppm TWA; 22 mg/m3 TWA Germany: Skin absorber Japan: 5 ppm OEL; 22 mg/m3 OEL Malaysia: 5 ppm TWA; 22 mg/m3 TWA Russia: 0.5 mg/m3 TWA Spain: 5 ppm VLA-ED; 22 mg/m3 VLA-ED CAS# 7732-18-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Aerosol
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula:
Molecular Weight:

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Cresols are slightly explosive in vapor form. They reacy vigorously with oxidizing materials. They react violently with nitric acid, oleum or chlorosulfonic acid.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 1319-77-3: GO5950000 CAS# 7732-18-5: ZC0110000 LD50/LC50:
CAS# 1319-77-3: Oral, mouse: LD50 = 760 mg/kg; Oral, mouse: LD50 = 860 mg/kg; Oral, rat: LD50 = 1454 mg/kg; Skin, rabbit: LD50 = 2 gm/kg; Skin, rabbit: LD50 = 200 mg/kg.
CAS# 7732-18-5: Oral, rat: LD50 = >90 mL/kg.
Carcinogenicity:
Cresols - Not listed by ACGIH, IARC, or NTP.
Water - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

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Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: DISINFECTANT, LIQUID, TOXIC, NOS
Hazard Class: 6.1
UN Number: 3142
Packing Group: II
IMO
Shipping Name: DISINFECTANT, LIQUID, TOXIC, NOS
Hazard Class: 6.1
UN Number: 3142
Packing Group: II
RID/ADR
Shipping Name: DISINFECTANT, LIQUID, TOXIC, NOS
Hazard Class: 6.1
UN Number: 3142
Packing group: II
USA RQ: CAS# 1319-77-3: 100 lb final RQ; 45.4 kg final RQ

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T C
Risk Phrases:
R 24/25 Toxic in contact with skin and if swallowed.
R 34 Causes burns.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28 After contact with skin, wash immediately
with...
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 1319-77-3: No information available.
CAS# 7732-18-5: No information available.
Canada
CAS# 1319-77-3 is listed on Canada's DSL List.
CAS# 7732-18-5 is listed on Canada's DSL List.
CAS# 1319-77-3 is listed on Canada's Ingredient Disclosure List.
CAS# 7732-18-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1319-77-3 is listed on the TSCA inventory.
CAS# 7732-18-5 is listed on the TSCA inventory.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

DATA ITEMS CITED :

44

MOLECULAR FORMULA :

C7-H8-O

MOLECULAR WEIGHT :

108.15

WISWESSER LINE NOTATION :

QR X1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human - man

DOSE/DURATION :

177 mg/kg

TOXIC EFFECTS :

Blood - other hemolysis with or without anemia Blood - other changes

REFERENCE :

CMAJAX Canadian Medical Association Journal. (Canadian Medical Assoc., POB 8650, Ottawa, ON K1G 0G8, Canada) V.1- 1911- Volume(issue)/page/year: 130,1319,1984

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Human

DOSE/DURATION :

114 mg/kg

TOXIC EFFECTS :

Vascular - other changes

REFERENCE :

85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,404,1989

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

1454 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB214-270

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

760 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

KSGZA3 Kyushu Shika Gakkai Zasshi. Journal of the Kyushu Dental Society. (c/o Kyushu Shika Daigaku, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu, Japan) V.1- 1933- Suspended 1941-50. Volume(issue)/page/year: 36,932,1982

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

2 gm/kg

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 42,417,1977 *** REVIEWS *** ACGIH TLV-TWA 22 mg/m3 (5 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 MSHA STANDARD:skin 5 ppm (22 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,61,1971 OSHA PEL (Gen Indu):8H TWA 5 ppm (22 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 5 ppm (22 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 5 ppm (22 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 5 ppm (22 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 5 ppm (23 mg/m3) JAN 1993 OEL-AUSTRALIA:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 5 ppm (22 mg/m3);STEL 10 ppm (44 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-GERMANY:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-HUNGARY:TWA 5 mg/m3;STEL 10 mg/m3 JAN 1993 OEL-INDIA:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-JAPAN:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-POLAND:TWA 5 mg/m3 JAN 1993 OEL-RUSSIA:TWA 5 ppm;STEL 0.5 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (22 mg/m3);STEL 10 ppm (44 mg/m3);Skin JAN 1993 OEL-TURKEY:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CRESOL, all isomers-air:10H TWA 2.3 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 20380 No. of Facilities: 8215 (estimated) No. of Industries: 86 No. of Occupations: 78 No. of Employees: 71952 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 20380 No. of Facilities: 7461 (estimated) No. of Industries: 84 No. of Occupations: 65 No. of Employees: 132742 (estimated) No. of Female Employees: 28184 (estimated)