Name | 7-chloro-3,3a-dihydro-2H-[1,2]oxazolo[3,2-b][1,3]benzoxazin-9-one |
---|---|
Synonyms |
Seclazonum [INN-Latin]
3,3a-Dihydro-7-chloro-2H,9H-isoxazolo(3,2-b)(1,3)benzoxazin-9-one Seclazona [INN-Spanish] Seclazone 7-chloro-3,3a-dihydro-2H-benzo[e]isoxazolo[3,2-b][1,3]oxazin-9-one W-2354 |
Description | Seclazone is a heterocyclic compound, possesses anti-inflammatory, analgesic, antipyretic and diuretic properties. Seclazone is orally bioavailable[1]. |
---|---|
Related Catalog | |
In Vivo | Seclazone (220 mg/kg; p.o.; dietary, daily) inhibits the development of adjuvant-induced polyarthritis in rats[1]. Seclazone significantly lowers the fever induced in rats by administration of a yeast suspension[1]. Animal Model: Male Charles River rats (150-170 g) [1] Dosage: 220 mg/kg Administration: Oral administration, dietary, daily Result: Inhibited adjuvant-induced polyarthritis |
References |
Molecular Formula | C10H8ClNO3 |
---|---|
Molecular Weight | 225.62800 |
Exact Mass | 225.01900 |
PSA | 38.77000 |
LogP | 1.77390 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
~% 29050-11-1 |
Literature: Reisner; Ludwig; Stiefel; Gister; Meyer; Powell; Sofia Arzneimittel-Forschung/Drug Research, 1977 , vol. 27, # 4 p. 760 - 766 |
~% 29050-11-1 |
Literature: Reisner; Ludwig; Stiefel; Gister; Meyer; Powell; Sofia Arzneimittel-Forschung/Drug Research, 1977 , vol. 27, # 4 p. 760 - 766 |
Precursor 2 | |
---|---|
DownStream 0 |