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122946-43-4

122946-43-4 structure
122946-43-4 structure
  • Name: Telmesteine
  • Chemical Name: (4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
  • CAS Number: 122946-43-4
  • Molecular Formula: C7H11NO4S
  • Molecular Weight: 205.23
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2018-06-03 08:00:00
  • Modify Date: 2024-01-17 10:26:34
  • Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].
Name (4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
Synonyms (R)-3-(Ethoxycarbonyl)thiazolidine-4-carboxylic acid
Telmesteinum
Telmesteine (INN)
Telmesteine
Telmesteina
(R)-thiazolidine-3,4-dicarboxylic acid-3-ethyl ester
Reolase (TN)
N-ethoxycarbonyl-D-thiazolidine-4-carboxylic acid
(R)-Thiazolidin-3,4-dicarbonsaeure-3-aethylester
Telmesteinum [INN-Latin]
UNII-124I3FE35T
Description Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].
Related Catalog
References

[1]. Lee J, et al. Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat. Xenobiotica. 2003 Jul;33(7):755-65.  

[2]. Xuetao Xu, et al. Evaluation of the anti-inflammatory properties of telmesteine on inflammation-associated skin diseases. RSC Adv., 2017, 7, 34699-34704.

Density 1.409g/cm3
Boiling Point 386.221ºC at 760 mmHg
Melting Point 98ºC
Molecular Formula C7H11NO4S
Molecular Weight 205.23
Flash Point 187.38ºC
Exact Mass 205.04100
PSA 92.14000
LogP 0.54030
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.562
HS Code 2934999090
541-41-3 structure

541-41-3

34592-47-7 structure

34592-47-7

~%

122946-43-4 structure

122946-43-4

Literature: Braibante, Mara E.F.; Braibante, Hugo S.; Costenaro, Edson R. Synthesis, 1999 , # 6 p. 943 - 946
541-41-3 structure

541-41-3

~%

122946-43-4 structure

122946-43-4

Literature: Strukow Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 521,523; engl. Ausg. S. 587, 589
Precursor  2

DownStream  0

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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title: CAS No. 122946-43-4 | Chemsrc address: https://m.chemsrc.com/en/baike/415506.html

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