Telmesteine

Modify Date: 2025-09-10 23:24:09

Telmesteine Structure
Telmesteine structure
Common Name Telmesteine
CAS Number 122946-43-4 Molecular Weight 205.23
Density 1.409g/cm3 Boiling Point 386.221ºC at 760 mmHg
Molecular Formula C7H11NO4S Melting Point 98ºC
MSDS N/A Flash Point 187.38ºC

 Use of Telmesteine


Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].

 Names

Name (4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
Synonym More Synonyms

 Telmesteine Biological Activity

Description Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].
Related Catalog
References

[1]. Lee J, et al. Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat. Xenobiotica. 2003 Jul;33(7):755-65.  

[2]. Xuetao Xu, et al. Evaluation of the anti-inflammatory properties of telmesteine on inflammation-associated skin diseases. RSC Adv., 2017, 7, 34699-34704.

 Chemical & Physical Properties

Density 1.409g/cm3
Boiling Point 386.221ºC at 760 mmHg
Melting Point 98ºC
Molecular Formula C7H11NO4S
Molecular Weight 205.23
Flash Point 187.38ºC
Exact Mass 205.04100
PSA 92.14000
LogP 0.54030
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.562

 Safety Information

HS Code 2934999090

 Synthetic Route

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Telmesteine Structure

Telmesteine

CAS#:122946-43-4

Literature: Braibante, Mara E.F.; Braibante, Hugo S.; Costenaro, Edson R. Synthesis, 1999 , # 6 p. 943 - 946

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Telmesteine Structure

Telmesteine

CAS#:122946-43-4

Literature: Strukow Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 521,523; engl. Ausg. S. 587, 589

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(R)-3-(Ethoxycarbonyl)thiazolidine-4-carboxylic acid
Telmesteinum
Telmesteine (INN)
Telmesteine
Telmesteina
(R)-thiazolidine-3,4-dicarboxylic acid-3-ethyl ester
Reolase (TN)
N-ethoxycarbonyl-D-thiazolidine-4-carboxylic acid
(R)-Thiazolidin-3,4-dicarbonsaeure-3-aethylester
Telmesteinum [INN-Latin]
UNII-124I3FE35T
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