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1347750-79-1

1347750-79-1 structure

1347750-79-1 structure

Name: HS-PEG3-CH2CH2N3
Chemical Name: 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethanethiol
CAS Number: 1347750-79-1
Molecular Formula: C₈H₁₇N₃O₃S
Molecular Weight: 235.30400
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-01-14 06:08:45
Modify Date: 2025-08-25 09:30:36
HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethanethiol

Description	HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₈H₁₇N₃O₃S
Molecular Weight	235.30400
Exact Mass	235.09900
PSA	116.24000
LogP	0.72906

Precursor 0
DownStream 1
31521-83-2

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