HS-PEG3-CH2CH2N3

Modify Date: 2024-01-10 20:03:04

HS-PEG3-CH2CH2N3 Structure
HS-PEG3-CH2CH2N3 structure
Common Name HS-PEG3-CH2CH2N3
CAS Number 1347750-79-1 Molecular Weight 235.30400
Density N/A Boiling Point N/A
Molecular Formula C8H17N3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HS-PEG3-CH2CH2N3


HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethanethiol

 HS-PEG3-CH2CH2N3 Biological Activity

Description HS-PEG3-CH2CH2N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C8H17N3O3S
Molecular Weight 235.30400
Exact Mass 235.09900
PSA 116.24000
LogP 0.72906

 Precursor & DownStream

Precursor  0

DownStream  1