Top Suppliers:I want be here


31521-83-2

31521-83-2 structure
31521-83-2 structure
  • Name: m-PEG3-SH
  • Chemical Name: 1-(1-Ethoxyethoxy)-2-methoxyethanethiol
  • CAS Number: 31521-83-2
  • Molecular Formula: C7H16O3S
  • Molecular Weight: 180.26500
  • Catalog: Chemical reagent Organic reagent Thiol salt
  • Create Date: 2019-01-02 11:53:12
  • Modify Date: 2024-01-21 11:52:52
  • m-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-(1-Ethoxyethoxy)-2-methoxyethanethiol
Synonyms 3,6,9-trioxadecanoic acid
1-mercapto-4,7,10-trioxaundecane
Description m-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.017
Molecular Formula C7H16O3S
Molecular Weight 180.26500
Exact Mass 180.08200
PSA 66.49000
LogP 1.28780
HS Code 2930909090

~78%

31521-83-2 structure

31521-83-2

Literature: Keddie, Daniel J.; Grande, John B.; Gonzaga, Ferdinand; Brook, Michael A.; Dargaville, Tim R. Organic Letters, 2011 , vol. 13, # 22 p. 6006 - 6009

~72%

31521-83-2 structure

31521-83-2

Literature: Ruizendaal, Loes; Pujari, Sidharam P.; Gevaerts, Veronique; Paulusse, Jos M. J.; Zuilhof, Han Chemistry - An Asian Journal, 2011 , vol. 6, # 10 p. 2776 - 2786

~%

31521-83-2 structure

31521-83-2

Literature: Keddie, Daniel J.; Grande, John B.; Gonzaga, Ferdinand; Brook, Michael A.; Dargaville, Tim R. Organic Letters, 2011 , vol. 13, # 22 p. 6006 - 6009

~65%

31521-83-2 structure

31521-83-2

Literature: Dabak, Salih; Ahsen, Vefa; Heinemann, Frauke; Zugenmaier, Peter Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2000 , vol. 348, p. 111 - 127

~%

31521-83-2 structure

31521-83-2

Literature: Gobbo, Pierangelo; Novoa, Samantha; Biesinger, Mark C.; Workentin, Mark S. Chemical Communications, 2013 , vol. 49, # 38 p. 3982 - 3984

~%

31521-83-2 structure

31521-83-2

Literature: Gobbo, Pierangelo; Novoa, Samantha; Biesinger, Mark C.; Workentin, Mark S. Chemical Communications, 2013 , vol. 49, # 38 p. 3982 - 3984

~%

31521-83-2 structure

31521-83-2

Literature: Gobbo, Pierangelo; Novoa, Samantha; Biesinger, Mark C.; Workentin, Mark S. Chemical Communications, 2013 , vol. 49, # 38 p. 3982 - 3984

~%

31521-83-2 structure

31521-83-2

Literature: Gobbo, Pierangelo; Novoa, Samantha; Biesinger, Mark C.; Workentin, Mark S. Chemical Communications, 2013 , vol. 49, # 38 p. 3982 - 3984

~%

31521-83-2 structure

31521-83-2

Literature: Gobbo, Pierangelo; Novoa, Samantha; Biesinger, Mark C.; Workentin, Mark S. Chemical Communications, 2013 , vol. 49, # 38 p. 3982 - 3984
HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%