128831-46-9
128831-46-9 structure
- Name: TMP-153
- Chemical Name: 1-[4-(2-chlorophenyl)-6,7-dimethylquinolin-3-yl]-3-(2,4-difluorophenyl)urea
- CAS Number: 128831-46-9
- Molecular Formula: C24H18ClF2N3O
- Molecular Weight: 437.869
- Create Date: 2016-03-01 15:26:22
- Modify Date: 2024-04-11 20:51:18
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TMP-153 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor with IC50 of 5-10 nM for the hepatic and intestinal ACAT from various animals.
| Name | 1-[4-(2-chlorophenyl)-6,7-dimethylquinolin-3-yl]-3-(2,4-difluorophenyl)urea |
|---|---|
| Synonyms |
CDQDU
Tmp 153 Urea, N-[4-(2-chlorophenyl)-6,7-dimethyl-3-quinolinyl]-N'-(2,4-difluorophenyl)- 1-[4-(2-Chlorophenyl)-6,7-dimethyl-3-quinolinyl]-3-(2,4-difluorophenyl)urea 1-[4-(2-Chlorophenyl)-6,7-dimethylquinolin-3-yl]-3-(2,4-difluorophenyl)urea |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 489.0±45.0 °C at 760 mmHg |
| Molecular Formula | C24H18ClF2N3O |
| Molecular Weight | 437.869 |
| Flash Point | 249.6±28.7 °C |
| Exact Mass | 437.110657 |
| PSA | 54.02000 |
| LogP | 6.97 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.687 |