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632-69-9

632-69-9 structure
632-69-9 structure
  • Name: Rose Bengal sodium
  • Chemical Name: Acid Red 94
  • CAS Number: 632-69-9
  • Molecular Formula: C20H2Cl4I4Na2O5
  • Molecular Weight: 1017.636
  • Catalog: Dyes and pigments dye Acid Dyestuff
  • Create Date: 2018-09-12 12:04:36
  • Modify Date: 2026-07-02 09:01:23
  • Rose Bengal sodium is a crimson-coloured dye, and it is a synthetic fluorescein derivative with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, it can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities[1][2].

Name Acid Red 94
Synonyms Eotaxin ELISA
goat IL-1βELISA
disodium (3-oxo-6-oxido-2,4,5,7-tetraiodo-3H-xanthen-9-yl)-3,4,5,6-tetrachlorobenzoate
ROSE BENGALE
Bengal Rose
MDC ELISA
Guinea Pig Histamine ELISA
FOOD RED NO
Spiro(isobenzofuran-1(3H),9’-(9H)xanthen)-3-one,4,5,6,7-tetrachloro-3’,6’-dihydroxy-2’,4’,5’,7’-tetraiodo,disodiumsalt
rosebengalsodium
Tetrachlorotetraiodofluorescein,disodiumsalt
Rose Bengal Sodium Salt
Guinea Pig IL-1 ELISA
MFCD00151169
SODIUM TETRAIODODICHLOROFLUORESCEIN
oxanthone2na
Food Red No. 105
benzoic acid, 2,3,4,5-tetrachloro-6-(6-hydroxy-2,4,5,7-tetraiodo-3-oxo-3H-xanthen-9-yl)-, disodium salt
CI 45440 SODIUM SALT
ROSE BENGAL SODIUM SALT
BENGAL ROSE B
ANILINE ROSE
Guinea Pig GM-CSF ELISA
UNII:956575SN5L
Guinea Pig IL-4 ELISA
dog IL-4 ELISA
LTC4 ELISA
BENGAL ROSE B SODIUM SALT
disodium 3,4,5,6-tetrachloro-2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl)benzoate
B RHODAMINE B
TETRAIODOTETRACHLOROFLUORESCEIN DISODIUM SALT
Red no. 105
dog IL-2 ELISA
Guinea pig IgE ELISA
Guinea Pig IFN-γ ELISA
4,5,6,7-tetrachloro-2’,4’,5’,7’-tetraiodo-fluoresceidisodiumsalt
4,5,6,7-TETRACHLORO-2',4',5',7'-TETRAIODOFLUORESCEIN SODIUM SALT
ENA-78 ELISA
dog TGF-βELISA
LTE4 ELISA
r105sodium
ROSE BENGAL DISODIUM SALT
Benzoic acid, 2,3,4,5-tetrachloro-6-(6-hydroxy-2,4,5,7-tetraiodo-3-oxo-3H-xanthen-9-yl)-, sodium salt (1:2)
LTD4 ELISA
Guinea Pig IL-5 ELISA
goat IFN-γELISA
dog sICAM-1 ELISA
ACID RED 94
foodredcolorno.105,sodiumsalt
dog MMP-9 ELISA
CI Acid red 94
TETRACHLOROTETRAIODOFLUORESCEIN SODIUM SALT
Guinea Pig IL-6 ELISA
CI NO
E-Cadherin ELISA
ROSE BENGAL 3B, CONC
foodredno.105,sodiumsalt
9-(3’,4’,5’,6’-tetrachloro-o-cboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3-is
LTB4 ELISA
BENGAL ROSE
Disodium 2,3,4,5-tetrachloro-6-(2,4,5,7-tetraiodo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
ROSE BENGAL G
Guinea Pig IL-2 ELISA
ROSE BENGAL
ROSE BENGAL B
4’,5’,7’-tetraiodo-droxy-2disodiumsalt
4,5,6,7-TETRACHLORO-2',4',5',7'-TETRAIODOFLUORESCEIN DISODIUM SALT
dog VCAM-1 ELISA
EINECS 211-182-8
Rozebengal,sodiumsalt
ACID RED 94 SODIUM SALT
Description Rose Bengal sodium is a crimson-coloured dye, and it is a synthetic fluorescein derivative with the principal component being 4,5,6,7-tetrachloro-2,4,5,7-tetraiodo fluorescein. Rose Bengal sodium has been widely used as an ophthalmic diagnostic agents, it can detect desiccated or damaged cells on the ocular surface. Rose Bengal sodium exhibits antiviral activities[1][2].
Related Catalog
References

[1]. Doughty MJ, et, al. Fluorescence characteristics of sodium fluorescein-rose bengal ophthalmic solution mixtures. Cont Lens Anterior Eye. 2014 Oct; 37(5): 358-62.

[2]. Roat MI, et, al. The antiviral effects of rose bengal and fluorescein. Arch Ophthalmol. 1987 Oct; 105(10): 1415-7.

Boiling Point 757.8ºC at 760 mmHg
Melting Point >300°C
Molecular Formula C20H2Cl4I4Na2O5
Molecular Weight 1017.636
Flash Point 412.1ºC
Exact Mass 1015.463013
PSA 93.40000
LogP 8.10410
Water Solubility soluble

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LM5920000
CHEMICAL NAME :
Fluorescein, 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-, disodium salt
CAS REGISTRY NUMBER :
632-69-9
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C20-H2-Cl4-I4-O5.2Na
MOLECULAR WEIGHT :
1017.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
707 gm/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Endocrine - thyroid tumors
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 77,277,1986 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
650 mg/kg
SEX/DURATION :
female 8-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 24,391,1982
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
400 mg/kg
SEX/DURATION :
female 8-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 24,391,1982
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
20 gm/kg
SEX/DURATION :
female 8-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 24,391,1982
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36
Safety Phrases S22-S24/25-S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LM5920000
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