122555-91-3

122555-91-3 structure

Name: DO3A tert-Butyl ester
Chemical Name: tert-butyl 2-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetate
CAS Number: 122555-91-3
Molecular Formula: C₂₆H₅₀N₄O₆
Molecular Weight: 514.698
Catalog: Research Areas Others
Create Date: 2018-11-11 02:26:23
Modify Date: 2025-08-20 07:07:47
DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride.

Name	tert-butyl 2-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetate
Synonyms	DO3A-t-Bu-ester 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, tris(1,1-dimethylethyl) ester 1,4,7-Tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane DO3A-tris-tbutyl ester 1,4,7,10-tetraazacyclododecane-1,4,7-tris(t-butyl acetate) TRI-T-BUTYL 1 4 7 10-TETRAAZACYCLODODECA DO3AtBu 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7-triacetate N',N",N'"-tris(t-Bu)DO3A 2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid tri-tert-butyl ester MFCD05865261 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid tris(1,1-dimethylethyl) ester DO3A-tris-tert-butyl ester Tris(2-methyl-2-propanyl) 2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate Tri-tert-butyl 2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate tert-butyl (1,4,7,10-tetraaza-4,7-bis(((tert-butyl)oxycarbonyl)methyl)cyclododecyl)acetate DO3A tert-Butyl ester

Description	DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
References	[1]. Martha L Gilbert, et al. A new synthetic route to 2-(p-nitrobenzyl)-1,4,7,10-tetraazacyclododecane. doi:10.1016/S0040-4039(00)73873-1

5292-43-3

294-90-6

~84%

122555-91-3

Literature: Tetrahedron Letters, , vol. 54, # 8 p. 918 - 920

107-59-5

294-90-6

~35%

122555-91-3

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 24 p. 7410 - 7413

5292-43-3

294-90-6

137145-75-6

122555-91-3

Detail

Literature: WO2005/32599 A1, ; Page/Page column 22-24; figure 12 ;

5292-43-3

294-90-6

~76%

122555-91-3

507475-91-4

Literature: WO2005/3105 A1, ; Page/Page column 6 ;

5292-43-3

10045-25-7

122555-91-3

Literature: Amino Acids, , vol. 46, # 2 p. 449 - 457