105454-04-4
105454-04-4 structure
- Name: 7-Epitaxol
- Chemical Name: 7-Epitaxol
- CAS Number: 105454-04-4
- Molecular Formula: C47H51NO14
- Molecular Weight: 853.906
- Catalog: Biochemical Plant extracts
- Create Date: 2018-02-06 08:00:00
- Modify Date: 2026-07-01 15:27:04
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7-epi-Taxol is an active metabolite of taxol, with activity comparable to that of taxol against cell replication, promoting microtubule bundle formation and against microtubule depolymerization.
| Name | 7-Epitaxol |
|---|---|
| Synonyms |
ITAXOL,7- SOLUTION(2.4mg/mL)(P)
Paclitaxel Impurity 5（Paclitaxel Impurity E） inhibit,Microtubule/Tubulin,7 i Taxol,7iTaxol,Inhibitor (2α,5β,7α,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate 5b,20-Epoxy-1,2a,4,7b,10b,13a-hexahydroxytax-11-en-9-one 4,10-Diacetate 2-Benzoate 13-Ester with (2R,3S)-N-Benzoyl-3-phenylisoserine Yewtaxan Paclitaxel Impurity E benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12B-bis(acetyloxy)-12-(benzoyloxy)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-dodecahydro-4,11-dihydroxy-4A,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-B)oxet-9-yl ester, (2- (2aalpha,4alpha,4abeta,6beta,9alpha(alph*,betas*),11alpha,12alpha,12aalpha,12balpha)) TaxAlbin Paclitaxel Impurity Ⅲ:(7-i-Paclitaxel) Paclitaxel 7-i-Impurity Epitaxol (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Bis(acetyloxy)-1,9-dihydroxy-15-({(2R,3S)-2-hydroxy-3-phenyl-3-[(phenylcarbonyl)amino]propanoyl}oxy)-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0.0]heptadec-13-en-2-ylbenzolcarboxylat 7-i-Taxol, 10 mM in DMSO Taxol A 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid derivative Paclitaxel Impurity E (7-Diverse Taxol) 7-i-Paclitaxel(7-itaxol) (2,4R,4aS,6R,9S,11S,12S,12,12bS)-9-(((2R,3S)-3-Benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2-[2aα,4α,4aβ,6β 7-epi-Taxol 7-itaxol 7-ipaclitaxel (2α,5β,7β,10β,13α)-4,10-bis(acetyloxy)-1,7-dihydroxy-13-({(2R,3S)-2-hydroxy-3-phenyl-3-[(phenylcarbonyl)amino]propanoyl}oxy)-9-oxo-5,20-epoxytax-11-en-2-yl benzoate UNII-P88XT4IS4D Paclitaxel Impurity E (7-i Paclitaxel) (1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-({(2R,3S)-2-hydroxy-3-phenyl-3-[(phenylcarbonyl)amino]propanoyl}oxy)-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0.0]heptadec-13-en-2-yl benzoate 7-ipaclitaxel, froM Taxus chinensis BMS 181339-01 7-i Paclitaxel (Paclitaxel Impurity E) itaxol Plaxicel Paxceed benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (2,4R,4as,6R,9S,11S,12S,12,12bs)-6,12B-bis(acetyloxy)-12-(benzoyloxy)- 2A,3,4,4A,5,6,9,10,11,12,12A,12B-dodecahydro-4,11-dihydroxy-4A,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-B)oxet-9-yl ester, (alph,betas) (2a,5b,7b,10b,13a)-4,10-bis(acetyloxy)-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate (2α,5β,7β,10β,13α)-4,10-Diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate 7-ipaclitaxel(crude) Paclitaxel (2,4R,4aS,6R,9S,11S,12S,12,12bS)-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1 7-ipaclitaxelQ: What is 7-ipaclitaxel Q: What is the CAS Number of 7-ipaclitaxel Q: What is the storage condition of 7-ipaclitaxel Q: What e the applications of 7-ipaclitaxel 7-itaxol ，S9265 7-ipaclitaxel from Taxus chinensis (Pilg.) Rehder Propanedioicacid,2-(2-propyn-6-yl)-,diethylester Peclitaxel Taxol ITAXOL, 7 Paxene Paclitaxel Imp. I : 10-O-[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]-10-O-deacetylpaclitaxel benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2,4R,4aS,6R,9S,11S,12S,12,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS) benzenepropanoicacid,beta-(benzoylaMino)-alpha-hydroxy-,6,12B-bis(acetyloxy)-12-(benzoyloxy)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-dodecahydro-4,11-dihydroxy-4A,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca(3,4)benz(1,2-B)oxet-9-ylester,(2-( 7-i-Taxol, Metabolite of Paclitaxel 7-IPACLITAXEL; 7-ITAXOL; 7-I-PACLITAXEL; ITAXOL LipoPac 7-Epi Paclitaxel Ebetaxel Anzatax baccatin III N-benzyl-b-phenylisoserine ester Onxol (2,4R,4aS,6R,9S,11S,12S,12,12bS)-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b-diyl diacetate |
| Description | 7-epi-Taxol is an active metabolite of taxol, with activity comparable to that of taxol against cell replication, promoting microtubule bundle formation and against microtubule depolymerization. |
|---|---|
| Related Catalog | |
| Target |
Microtubule/Tubulin[2] |
| In Vitro | 7-epi-Taxol (7-Epitaxol) is a metabolite of taxol[1]. 7-epi-Taxol has activity comparable to that of taxol on cell replication, microtubule bundle formation and in vitro microtubule polymerization[2]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 957.1±65.0 °C at 760 mmHg |
| Melting Point | 168-170?C |
| Molecular Formula | C47H51NO14 |
| Molecular Weight | 853.906 |
| Flash Point | 532.6±34.3 °C |
| Exact Mass | 853.330933 |
| PSA | 221.29000 |
| LogP | 7.38 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.637 |
| Storage condition | -20°C Freezer, Under Inert Atmosphere |
| HS Code | 2932999026 |
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| Precursor 0 | |
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| DownStream 2 | |
| HS Code | 2932999026 |
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