4928-02-3

4928-02-3 structure

4928-02-3 structure

Name: 7-aminonitrazepam
Chemical Name: 7-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
CAS Number: 4928-02-3
Molecular Formula: C₁₅H₁₃N₃O
Molecular Weight: 251.28300
Catalog: analytical chemistry Standard standard material
Create Date: 2018-09-17 06:20:11
Modify Date: 2024-01-04 08:08:41

Name	7-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
Synonyms	7-Amino-1,2-dihydro-3H-1,4-benzodiazepin-2-one 7-Amino-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin 7-Amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one 7-Amino-2-oxo-5-phenyl-2,3-dihydro-1H-benzo<e>-1,4-diazepin 7-amino-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one 7-Amino Nitrazepam Ro 5-3072 7-Amino-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one 2H-1,4-Benzodiazepin-2-one,7-amino-1,3-dihydro-5-phenyl 7-amino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one 7-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepinon-(2) 7-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Density	1.3g/cm3
Boiling Point	495.8ºC at 760 mmHg
Melting Point	242-244ºC
Molecular Formula	C₁₅H₁₃N₃O
Molecular Weight	251.28300
Flash Point	253.6ºC
Exact Mass	251.10600
PSA	67.48000
LogP	2.21310
Index of Refraction	1.683

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE9750000

CHEMICAL NAME :: 2H-1,4-Benzodiazepin-2-one, 7-amino-1,3-dihydro-5-phenyl-

CAS REGISTRY NUMBER :: 4928-02-3

BEILSTEIN REFERENCE NO. :: 0535813

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H13-N3-O

MOLECULAR WEIGHT :: 251.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 300 mg/kg

SEX/DURATION :: female 12 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 44,209,1991

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H225-H302 + H332-H319
Precautionary Statements	P210-P305 + P351 + P338
Hazard Codes	F,Xn
Risk Phrases	11-20/21/22-36
Safety Phrases	16-36/37
RIDADR	UN 1648 3 / PGII

146-22-5 structure

146-22-5

~88%

4928-02-3 structure

4928-02-3

Literature: Severino, Beatrice; Fiorino, Ferdinando; Perissutti, Elisa; Frecentese, Francesco; Cirino, Giuseppe; Roviezzo, Fiorentina; Santagada, Vincenzo; Caliendo, Giuseppe Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 11 p. 6009 - 6020

Precursor 1
146-22-5
DownStream 0