7-aminonitrazepam

Modify Date: 2024-01-04 08:08:41

7-aminonitrazepam Structure
7-aminonitrazepam structure
Common Name 7-aminonitrazepam
CAS Number 4928-02-3 Molecular Weight 251.28300
Density 1.3g/cm3 Boiling Point 495.8ºC at 760 mmHg
Molecular Formula C15H13N3O Melting Point 242-244ºC
MSDS N/A Flash Point 253.6ºC
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Names

Name 7-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3g/cm3
Boiling Point 495.8ºC at 760 mmHg
Melting Point 242-244ºC
Molecular Formula C15H13N3O
Molecular Weight 251.28300
Flash Point 253.6ºC
Exact Mass 251.10600
PSA 67.48000
LogP 2.21310
Index of Refraction 1.683

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DE9750000
CHEMICAL NAME :
2H-1,4-Benzodiazepin-2-one, 7-amino-1,3-dihydro-5-phenyl-
CAS REGISTRY NUMBER :
4928-02-3
BEILSTEIN REFERENCE NO. :
0535813
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H13-N3-O
MOLECULAR WEIGHT :
251.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
300 mg/kg
SEX/DURATION :
female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 44,209,1991

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H302 + H332-H319
Precautionary Statements P210-P305 + P351 + P338
Hazard Codes F,Xn
Risk Phrases 11-20/21/22-36
Safety Phrases 16-36/37
RIDADR UN 1648 3 / PGII

 Precursor & DownStream

Precursor  1

DownStream  0

 Articles10

More Articles
Measurement of benzodiazepines in urine by liquid chromatography-tandem mass spectrometry: confirmation of samples screened by immunoassay.

Ann. Clin. Biochem. 47(Pt 2) , 111-7, (2010)

Liquid chromatography linked to tandem mass spectrometry (LC/MS/MS) provides the ability to identify a range of benzodiazepines in accordance with European Union criteria and is an attractive method f...

A highly sensitive method for the determination of 7-aminonitrazepam, a metabolite of nitrazepam, in human urine using high-performance electrospray liquid chromatography tandem mass spectrometry.

Biomed. Chromatogr. 23(7) , 740-4, (2009)

A highly sensitive method has been developed for the determination of urinary 7-aminonitrazepam (7-ANZP), the major metabolite of nitrazepam, using high-performance electrospray liquid chromatography ...

Determination of nitrazepam and its main metabolites in urine by thin-layer chromatography and direct densitometry.

J. Chromatogr. A. 339(1) , 163-9, (1985)

A method for the direct quantitative densitometry of nitrazepam and its main metabolites (7-aminonitrazepam, 7-acetamidonitrazepam and 2-amino-5-nitrobenzophenone) in urine was developed. The unchange...

 Synonyms

7-Amino-1,2-dihydro-3H-1,4-benzodiazepin-2-one
7-Amino-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin
7-Amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
7-Amino-2-oxo-5-phenyl-2,3-dihydro-1H-benzo<e>-1,4-diazepin
7-amino-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one
7-Amino Nitrazepam
Ro 5-3072
7-Amino-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one
2H-1,4-Benzodiazepin-2-one,7-amino-1,3-dihydro-5-phenyl
7-amino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one
7-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepinon-(2)
7-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one