137089-36-2
137089-36-2 structure
- Name: 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
- Chemical Name: (E)-N-[2-(2-cyclohexylethylsulfanyl)ethyl]dec-2-enamide
- CAS Number: 137089-36-2
- Molecular Formula: C20H37NOS
- Molecular Weight: 339.57900
- Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
- Create Date: 2016-12-02 11:26:00
- Modify Date: 2024-01-10 21:32:00
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2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.
| Name | (E)-N-[2-(2-cyclohexylethylsulfanyl)ethyl]dec-2-enamide |
|---|---|
| Synonyms |
2-Decenamide,N-(2-((2-cyclohexylethyl)thio)ethyl)-,(E)
2-(E-2-decenoylamino)ethyl 2-cyclohexylethyl sulfide 2-Deces 2-(2-Decenoylamino)ethyl-2-(cyclohexylethyl)sulfide 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide |
| Description | 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress. |
|---|---|
| Related Catalog | |
| Target |
PGE2 PGI2 PLA2 |
| In Vivo | 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (compd.III-1α, 100 mg/kg, p.o.) maintains the relative content of Fr.I hexose, lipid peroxide and phospholipase A2 (PLA2) in normal level in ulcerated rats induced by water immersed restrained stress via dosing twice a day for 3 day (b.i.d. for 3 d). 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (100 mg/kg, p.o.) reduces the hexosamine content equally with the control group 4 h after the stress loading, and then markedly increases 7 h after stress loading. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) blocks the reduction of prostaglandin E2 (PGE2) and PGI2 in early phase and accelerates the increase of PGE2 and PGI2 in the late phase of the stress. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide (25 mg/kg, p.o.) also significantly accelerates the cell proliferation in fundic glands in gastric mucosa of mice[1]. |
| References |
| Density | 0.954g/cm3 |
|---|---|
| Boiling Point | 503.3ºC at 760 mmHg |
| Molecular Formula | C20H37NOS |
| Molecular Weight | 339.57900 |
| Flash Point | 258.2ºC |
| Exact Mass | 339.26000 |
| PSA | 57.89000 |
| LogP | 6.56320 |
| Vapour Pressure | 2.93E-10mmHg at 25°C |
| Index of Refraction | 1.498 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |