134332-50-6

134332-50-6 structure
134332-50-6 structure
  • Name: Galanthamine 10-Oxide(Galanthamine N-Oxide)
  • Chemical Name: Galanthamine N-Oxide
  • CAS Number: 134332-50-6
  • Molecular Formula: C17H21NO4
  • Molecular Weight: 303.35300
  • Catalog: Signaling Pathways Neuronal Signaling AChE
  • Create Date: 2016-03-02 16:37:04
  • Modify Date: 2024-01-21 13:08:21
  • Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2].

Name Galanthamine N-Oxide
Synonyms Nivalin-oxide
(4aS,6R,8aS,11R)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-Oxide
galanthamine-N-oxide
Galanthamine 10-Oxide
N-Oxide Galantamine
Galanthamine |A-N-oxide
Description Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2].
Related Catalog
References

[1]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33.

[2]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33.

Melting Point 246-247ºC
Molecular Formula C17H21NO4
Molecular Weight 303.35300
Exact Mass 303.14700
PSA 68.12000
LogP 1.82170
Hazard Codes Xi