134332-50-6
134332-50-6 structure
- Name: Galanthamine 10-Oxide(Galanthamine N-Oxide)
- Chemical Name: Galanthamine N-Oxide
- CAS Number: 134332-50-6
- Molecular Formula: C17H21NO4
- Molecular Weight: 303.35300
- Catalog: Signaling Pathways Neuronal Signaling AChE
- Create Date: 2016-03-02 16:37:04
- Modify Date: 2026-07-02 19:12:15
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Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2].
| Name | Galanthamine N-Oxide |
|---|---|
| Synonyms |
(4aS,6R,8aS,11R)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-Oxide
Inhibitor,substrate,Galanthamine N Oxide,Galanthamine NOxide,alkaloid,site,active,accommodation,Cholinesterase (ChE),Galanthamine N-Oxide,inhibit Galanthamine-N-oxide(11R-Isomer) Galanthamine 10-Oxide 6H-Benzofuro[3a,3,2-ef]benzazin-6-ol, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, 11-oxide, (4aS,6R,8aS,11R) galanthamine-N-oxide Galanthamine |A-N-oxide Nivalin-oxide Galantamine Impurity N-Oxide (4aS,6R,8aS,11R)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef]benzazin-6-ol 11-Oxide Eicosapentaenoic Acid Impurity 26 Galantamine Impurity 10 N-Oxide Galantamine Galantamine N-Oxide Impurity Galanthamine N-Oxide, 10 mM in DMSO |
| Description | Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2]. |
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| Related Catalog | |
| References |
| Melting Point | 246-247ºC |
|---|---|
| Molecular Formula | C17H21NO4 |
| Molecular Weight | 303.35300 |
| Exact Mass | 303.14700 |
| PSA | 68.12000 |
| LogP | 1.82170 |
| Hazard Codes | Xi |
|---|
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134332-50-6 |
| Literature: Kobayashi, Shigeru; Satoh, Kimihito; Numata, Atsushi; Shingu, Tetsuro; Kihara, Masaru Phytochemistry (Elsevier), 1991 , vol. 30, # 2 p. 675 - 677 |
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134332-50-6 |
| Literature: Phytochemistry (Elsevier), , vol. 30, # 2 p. 675 - 677 |
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~%
134332-50-6 |
| Literature: Kobayashi, Shigeru; Satoh, Kimihito; Numata, Atsushi; Shingu, Tetsuro; Kihara, Masaru Phytochemistry (Elsevier), 1991 , vol. 30, # 2 p. 675 - 677 |
| Precursor 3 | |
|---|---|
| DownStream 1 | |
