Galanthamine 10-Oxide(Galanthamine N-Oxide)

Modify Date: 2024-01-21 13:08:21

Galanthamine 10-Oxide(Galanthamine N-Oxide) Structure
Galanthamine 10-Oxide(Galanthamine N-Oxide) structure
Common Name Galanthamine 10-Oxide(Galanthamine N-Oxide)
CAS Number 134332-50-6 Molecular Weight 303.35300
Density N/A Boiling Point N/A
Molecular Formula C17H21NO4 Melting Point 246-247ºC
MSDS N/A Flash Point N/A

 Use of Galanthamine 10-Oxide(Galanthamine N-Oxide)


Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2].

 Names

Name Galanthamine N-Oxide
Synonym More Synonyms

  Biological Activity

Description Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes[1][2].
Related Catalog
References

[1]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33.

[2]. Reyes-Chilpa R, et al. Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor. Molecules. 2011 Nov 15;16(11):9520-33.

 Chemical & Physical Properties

Melting Point 246-247ºC
Molecular Formula C17H21NO4
Molecular Weight 303.35300
Exact Mass 303.14700
PSA 68.12000
LogP 1.82170

 Safety Information

Hazard Codes Xi

 Synonyms

Nivalin-oxide
(4aS,6R,8aS,11R)-4a,5,9,10,11,12-Hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-ol 11-Oxide
galanthamine-N-oxide
Galanthamine 10-Oxide
N-Oxide Galantamine
Galanthamine |A-N-oxide