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129724-43-2

129724-43-2 structure
129724-43-2 structure
  • Name: 2',4'-Dihydroxy-3',6'-dimethoxychalcone
  • Chemical Name: (2E)-1-(2,4-Dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-2-propen-1-on e
  • CAS Number: 129724-43-2
  • Molecular Formula: C17H16O5
  • Molecular Weight: 300.306
  • Catalog: Natural product Chalcone
  • Create Date: 2018-06-21 23:50:50
  • Modify Date: 2024-01-18 17:39:58
  • 2',4'-Dihydroxy-3',6'-dimethoxychalcone is a natural product that can be isolated from Polygonum Lapathifolium. 2',4'-Dihydroxy-3',6'-dimethoxychalcone inhibits the growth of CCRF-CEM leukaemia cells and CEM/ADR5000 cells, with IC50 values of 10.67 and 18.60 μM, respectively[1][2].

Name (2E)-1-(2,4-Dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-2-propen-1-on e
Synonyms (2Z)-1-(2,4-Dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-2-propen-1-one
2',4'-dihydroxy-3',6'-dimethoxychalcone
2-Propen-1-one, 1-(2,4-dihydroxy-3,6-dimethoxyphenyl)-3-phenyl-, (2Z)-
Benzaldehyde,2,4-dihydroxy-3,5-dimethoxy
Description 2',4'-Dihydroxy-3',6'-dimethoxychalcone is a natural product that can be isolated from Polygonum Lapathifolium. 2',4'-Dihydroxy-3',6'-dimethoxychalcone inhibits the growth of CCRF-CEM leukaemia cells and CEM/ADR5000 cells, with IC50 values of 10.67 and 18.60 μM, respectively[1][2].
Related Catalog
References

[1]. Ahmed M, et al. Isoflavan-4-ol, dihydrochalcone and chalcone derivatives from Polygonum Lapathifolium. Phytochemistry, 1990, 29(6):2009-2011.

[2]. Nkuété AH, et al. Anti-leukemia activity of semi-synthetic phenolic derivatives from Polygonum limbatum Meisn. Chem Cent J. 2015 Jun 24;9:40.

Density 1.3±0.1 g/cm3
Boiling Point 556.0±50.0 °C at 760 mmHg
Molecular Formula C17H16O5
Molecular Weight 300.306
Flash Point 207.3±23.6 °C
Exact Mass 300.099762
PSA 75.99000
LogP 3.41
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.637
Hazard Codes Xi
HS Code 2914509090
Precursor  2

DownStream  1

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%