1394854-51-3
1394854-51-3 structure
- Name: GSK-J5
- Chemical Name: Ethyl N-[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3- yl)-4-pyrimidinyl]-β-alaninate
- CAS Number: 1394854-51-3
- Molecular Formula: C24H27N5O2
- Molecular Weight: 417.50
- Catalog: Signaling Pathways Epigenetics Histone Demethylase
- Create Date: 2017-10-27 13:57:49
- Modify Date: 2024-01-12 21:25:25
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GSK-J5 is a potent inhibitor of Schistosome and worm. GSK-J5 increases schistosomula mortality and adult worm motility and mortality, as well as egg oviposition, in a dose- and time-dependent manner[1].
| Name | Ethyl N-[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3- yl)-4-pyrimidinyl]-β-alaninate |
|---|---|
| Synonyms |
β-Alanine, N-[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-, ethyl ester
Ethyl N-[2-(3-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alaninate |
| Description | GSK-J5 is a potent inhibitor of Schistosome and worm. GSK-J5 increases schistosomula mortality and adult worm motility and mortality, as well as egg oviposition, in a dose- and time-dependent manner[1]. |
|---|---|
| Related Catalog | |
| References |
[3]. Heinemann B, et al. Inhibition of demethylases by GSK-J1/J4. Nature. 2014 Oct 2;514(7520):E1-2 |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 581.2±50.0 °C at 760 mmHg |
| Molecular Formula | C24H27N5O2 |
| Molecular Weight | 417.50 |
| Flash Point | 305.3±30.1 °C |
| Exact Mass | 417.216461 |
| PSA | 80.24000 |
| LogP | 3.75 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.615 |