492445-28-0
492445-28-0 structure
- Name: PHA690509
- Chemical Name: (2S)-2-(4-Acetamidophenyl)-N-(5-isopropyl-1,3-thiazol-2-yl)propan amide
- CAS Number: 492445-28-0
- Molecular Formula: C17H21N3O2S
- Molecular Weight: 331.432
- Catalog: Signaling Pathways Apoptosis Caspase
- Create Date: 2017-11-04 05:58:48
- Modify Date: 2025-09-02 19:13:41
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PHA-690509 is an anti-ZikV compound that inhibits ZikV replication. PHA-690509 is also a CDK inhibitor, and inhibits caspase-3 activity[1][2].
| Name | (2S)-2-(4-Acetamidophenyl)-N-(5-isopropyl-1,3-thiazol-2-yl)propan amide |
|---|---|
| Synonyms |
(2S)-2-(4-Acetamidophenyl)-N-(5-isopropyl-1,3-thiazol-2-yl)propanamide
(2S)-2-[(2-fluorophenyl)methyl]-3-(2-fluorospiro[4,5-dihydrothieno-[2,3-c]pyran-7,4'-piperidine]-1'-yl)-N-methylpropanamide NOP-1A (2S)-2-[4-(acetylamino)phenyl]-N-(5-isopropyl-1,3-thiazol-2-yl)propanamide Benzeneacetamide, 4-(acetylamino)-α-methyl-N-[5-(1-methylethyl)-2-thiazolyl]-, (αS)- (2S)-2-[(3,6-diethylpyrazin-2-yl)amino]butan-1-ol |
| Description | PHA-690509 is an anti-ZikV compound that inhibits ZikV replication. PHA-690509 is also a CDK inhibitor, and inhibits caspase-3 activity[1][2]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C17H21N3O2S |
| Molecular Weight | 331.432 |
| Exact Mass | 331.135437 |
| PSA | 106.31000 |
| LogP | 3.09 |
| Index of Refraction | 1.629 |
|
~%
492445-28-0 |
| Literature: Pevarello, Paolo; Amici, Raffaella; Villa, Manuela; Solom, Barbara; Vulpetti, Anna; Varasi, Mario; Brasca, Maria Gabriella; Traquandi, Gabriella; Nesi, Marcella Patent: US2004/235919 A1, 2004 ; US 20040235919 A1 |
