496775-95-2
496775-95-2 structure
- Name: ML-099
- Chemical Name: 2-(2-phenylethylsulfanyl)pyridine-3-carboxylic acid
- CAS Number: 496775-95-2
- Molecular Formula: C14H13NO2S
- Molecular Weight: 259.323
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2016-05-30 13:56:39
- Modify Date: 2024-01-09 17:57:56
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ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A[1].
| Name | 2-(2-phenylethylsulfanyl)pyridine-3-carboxylic acid |
|---|---|
| Synonyms |
2-[(2-Phenylethyl)sulfanyl]nicotinic acid
3-Pyridinecarboxylic acid, 2-[(2-phenylethyl)thio]- |
| Description | ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A[1]. |
|---|---|
| Related Catalog | |
| In Vitro | ML-099 activates cell division cycle 42 activated mutant, cell division cycle 42 wild type, Ras protein wild type, GTP-binding protein (Rab7), Rab-2A, Rac1 protein activated mutant, Rac1 protein wild type, and Ras protein activated mutant with EC50 values of 58.88 nM, 100 nM, 141.25 nM, 181.97 nM, 354.81 nM, 25.42 nM, 20.17 nM and 95.5 nM, respectively[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 449.1±40.0 °C at 760 mmHg |
| Molecular Formula | C14H13NO2S |
| Molecular Weight | 259.323 |
| Flash Point | 225.4±27.3 °C |
| Exact Mass | 259.066711 |
| PSA | 75.49000 |
| LogP | 3.43 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.646 |
| RIDADR | NONH for all modes of transport |
|---|---|
| HS Code | 2933399090 |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |