ML-099
Modify Date: 2025-08-25 06:44:11
ML-099 structure
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Common Name | ML-099 | ||
|---|---|---|---|---|
| CAS Number | 496775-95-2 | Molecular Weight | 259.323 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 449.1±40.0 °C at 760 mmHg | |
| Molecular Formula | C14H13NO2S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 225.4±27.3 °C | |
Use of ML-099ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A[1]. |
| Name | 2-(2-phenylethylsulfanyl)pyridine-3-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | ML-099 (CID-888706) is a pan Ras-related GTPases activator that can activate Rac1, cell division cycle 42, Ras, Rab7, and Rab-2A[1]. |
|---|---|
| Related Catalog | |
| In Vitro | ML-099 activates cell division cycle 42 activated mutant, cell division cycle 42 wild type, Ras protein wild type, GTP-binding protein (Rab7), Rab-2A, Rac1 protein activated mutant, Rac1 protein wild type, and Ras protein activated mutant with EC50 values of 58.88 nM, 100 nM, 141.25 nM, 181.97 nM, 354.81 nM, 25.42 nM, 20.17 nM and 95.5 nM, respectively[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 449.1±40.0 °C at 760 mmHg |
| Molecular Formula | C14H13NO2S |
| Molecular Weight | 259.323 |
| Flash Point | 225.4±27.3 °C |
| Exact Mass | 259.066711 |
| PSA | 75.49000 |
| LogP | 3.43 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.646 |
| InChIKey | UZERZZRWECLIKE-UHFFFAOYSA-N |
| SMILES | O=C(O)c1cccnc1SCCc1ccccc1 |
| RIDADR | NONH for all modes of transport |
|---|---|
| HS Code | 2933399090 |
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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|
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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|
Name: Dose response of compounds that promote myeloid differentiation with HOXA9ER cells wi...
Source: NMMLSC
External Id: UNMCMD_HOXA9_MYELOIDDIFFERENTIATION_HOXA9ER_SAR01
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|
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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|
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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|
Name: Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste...
Source: Broad Institute
Target: N/A
External Id: 7124-01_Inhibitor_SinglePoint_HTS_Activity
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|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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| 2-[(2-Phenylethyl)sulfanyl]nicotinic acid |