143393-27-5

143393-27-5 structure

Name: 4-({[(2S,4S)-2-[2-(4-Chlorophenyl)ethyl]-2-(1H-imidazol-1-ylmethy l)-1,3-dioxolan-4-yl]methyl}sulfanyl)aniline
Chemical Name: 4-({[(2S,4S)-2-[2-(4-Chlorophenyl)ethyl]-2-(1H-imidazol-1-ylmethy l)-1,3-dioxolan-4-yl]methyl}sulfanyl)aniline
CAS Number: 143393-27-5
Molecular Formula: C₂₂H₂₄ClN₃O₂S
Molecular Weight: 429.96300
Create Date: 2018-03-27 08:00:00
Modify Date: 2024-04-02 09:04:39

Name	4-({[(2S,4S)-2-[2-(4-Chlorophenyl)ethyl]-2-(1H-imidazol-1-ylmethy l)-1,3-dioxolan-4-yl]methyl}sulfanyl)aniline
Synonyms	(2S,4S)-6-Fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxylic acid 2-propyl ester (2S,4S)-azalanstat (2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazol-1-yl)methyl]-[{(4-aminophenyl)thio}methyl]-1,3-dioxolane (2S,4S)-Propyl 6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxylate (2S,4S)-cis-2-(2-(4-chlorophenyl)ethyl)-2-(imidazol-1-yl)methyl-4-(4-aminophenylthio)methyl-1,3-dioxolane (2S,4S)-6-fluoro-2,3-dihydro-2',5'-dioxospiro<4H-1-benzopyran-4,4'-imidazolidine>-2-carboxylic acid n-propyl ester (2S,4S)-6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxylic acid n-propyl ester Azetrenatat

Density	1.31g/cm3
Boiling Point	647.7ºC at 760mmHg
Molecular Formula	C₂₂H₂₄ClN₃O₂S
Molecular Weight	429.96300
Flash Point	345.5ºC
Exact Mass	429.12800
PSA	87.60000
LogP	5.23670
Vapour Pressure	1.16E-16mmHg at 25°C
Index of Refraction	1.644

143327-62-2

1193-02-8

~87%

143393-27-5

Literature: Syntex (U.S.A.) Inc. Patent: US5208331 A1, 1993 ;

1336-21-6

143327-62-2

1193-02-8

~85%

143393-27-5

Literature: Syntex (U.S.A.) Inc. Patent: US5158949 A1, 1992 ;

23735-43-5

143393-27-5

Literature: Walker; Kertesz; Rotstein; Swinney; Berry; So -; Webb; Watson; Mak; Burton; Mills-Dunlap; Chiou; Tokes; Kurz; Kern; Chan; Salari; Mendizabal Journal of Medicinal Chemistry, 1993 , vol. 36, # 15 p. 2235 - 2237

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