152015-61-7

152015-61-7 structure

Name: benzyloxycarbonylleucyl-leucyl-leucyl-4-methyl-coumaryl-7-amide
Chemical Name: benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-2-[(4-methyl-2-oxochromen-7-yl)amino]pentanoyl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
CAS Number: 152015-61-7
Molecular Formula: C₃₆H₄₈N₄O₇
Molecular Weight: 648.78900
Catalog: Signaling Pathways Metabolic Enzyme/Protease Proteasome
Create Date: 2016-06-19 11:56:38
Modify Date: 2025-08-25 18:23:39
Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome[1].

Name	benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-2-[(4-methyl-2-oxochromen-7-yl)amino]pentanoyl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Synonyms	Zlll-mca Z-Leu-leu-leu-4-methylcoumaryl-7-amide Benzyloxycarbonylleucyl-leucyl-leucyl-4-methyl-coumaryl-7-amide L-Leucinamide,N-((phenylmethoxy)carbonyl)-L-leucyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)

Description	Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome
References	[1]. McNaught KS, et al. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett. 2001 Jan 19;297(3):191-4.