77111-29-6

77111-29-6 structure

Name: NSC 295642
Chemical Name: (E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane,chlorocopper(1+)
CAS Number: 77111-29-6
Molecular Formula: C₁₅H₁₄ClCuN₃S₂
Molecular Weight: 399.42100
Catalog: Signaling Pathways Cell Cycle/DNA Damage PERK
Create Date: 2016-03-22 18:30:30
Modify Date: 2024-01-09 19:29:29
NSC 295642 is a phosphatase inhibitor. NSC 295642 can significantly increase phospho-Erk cytonuclear differences in intact cells. NSC 295642 can be used for the research of cancer[1].

Name	(E)-benzylsulfanyl-[(E)-1-pyridin-2-ylethylidenehydrazinylidene]-sulfidomethane,chlorocopper(1+)

Description	NSC 295642 is a phosphatase inhibitor. NSC 295642 can significantly increase phospho-Erk cytonuclear differences in intact cells. NSC 295642 can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Signaling Pathways >> Cell Cycle/DNA Damage >> PERK
In Vitro	NSC 295642 (10 μM) 抑制 MKP-3 (PYST-1) 50% 或更多[1]。 NSC 295642 抑制 Cdc25A 的催化结构域[1]。 NSC 295642 对缺少调节 N 末端的截短形式的 Cdc25B 具有活性[1]。
References	[1]. Andreas Vogt, et al. Cell-active dual specificity phosphatase inhibitors identified by high-content screening. Chem Biol. 2003 Aug;10(8):733-42.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
RIDADR	NONH for all modes of transport