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85136-58-9

85136-58-9 structure
85136-58-9 structure
  • Name: Bis-acrylate-PEG6
  • Chemical Name: 2-[2-[2-[2-[2-(2-prop-2-enoyloxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl prop-2-enoate
  • CAS Number: 85136-58-9
  • Molecular Formula: C18H30O9
  • Molecular Weight: 390.42500
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-09-16 03:41:40
  • Modify Date: 2024-01-03 15:47:41
  • Bis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-[2-[2-[2-[2-(2-prop-2-enoyloxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl prop-2-enoate
Synonyms EINECS 285-782-3
2-Propenoic acid,1,1'-(3,6,9,12,15-pentaoxaheptadecane-1,17-diyl) ester
2-Propenoicacid,3,6,9,12,15-pentaoxaheptadecane-1,17-diyl ester (9CI)
Hexaethyleneglycoldiacrylate
3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl diacrylate
Description Bis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.101g/cm3
Boiling Point 459.125ºC at 760 mmHg
Molecular Formula C18H30O9
Molecular Weight 390.42500
Flash Point 196.816ºC
Exact Mass 390.18900
PSA 98.75000
LogP 0.52780
Index of Refraction 1.46
Hazard Codes Xi