Bis-acrylate-PEG6

Modify Date: 2025-08-27 16:52:36

Bis-acrylate-PEG6 Structure
Bis-acrylate-PEG6 structure
Common Name Bis-acrylate-PEG6
CAS Number 85136-58-9 Molecular Weight 390.42500
Density 1.101g/cm3 Boiling Point 459.125ºC at 760 mmHg
Molecular Formula C18H30O9 Melting Point N/A
MSDS N/A Flash Point 196.816ºC

 Use of Bis-acrylate-PEG6


Bis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-[2-(2-prop-2-enoyloxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl prop-2-enoate
Synonym More Synonyms

 Bis-acrylate-PEG6 Biological Activity

Description Bis-acrylate-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.101g/cm3
Boiling Point 459.125ºC at 760 mmHg
Molecular Formula C18H30O9
Molecular Weight 390.42500
Flash Point 196.816ºC
Exact Mass 390.18900
PSA 98.75000
LogP 0.52780
Index of Refraction 1.46
InChIKey DMMSYVRRDYJQSI-UHFFFAOYSA-N
SMILES C=CC(=O)OCCOCCOCCOCCOCCOCCOC(=O)C=C

 Safety Information

Hazard Codes Xi

 Synonyms

EINECS 285-782-3
2-Propenoic acid,1,1'-(3,6,9,12,15-pentaoxaheptadecane-1,17-diyl) ester
2-Propenoicacid,3,6,9,12,15-pentaoxaheptadecane-1,17-diyl ester (9CI)
Hexaethyleneglycoldiacrylate
3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl diacrylate
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