2156-29-8
2156-29-8 structure
- Name: 2-di-1-asp
- Chemical Name: 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide
- CAS Number: 2156-29-8
- Molecular Formula: C16H19IN2
- Molecular Weight: 366.24000
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Methylpyridine
- Create Date: 2018-12-24 15:36:03
- Modify Date: 2024-01-04 12:02:36
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2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1].
| Name | 2-[4-(dimethylamino)styryl]-1-methylpyridinium iodide |
|---|---|
| Synonyms |
D-308
2-{2-[4-(dimethylamino)phenyl]ethenyl}-1-methylpyridinium iodide 2m2Pm 2-(4-(Dimethylamino)styryl)-N-methylpyridinium MFCD00011980 o-DPD 2-<4-(dimethylamino)styryl>-1-ethylpyridinium iodide 2-(4-(dimethylamino)styryl)-1-methylpyridinium (E)-2-(4-(dimethylamino)styryl)-1-methylpyridinium iodide 2-(4-DIMETHYLAMINOSTYRYL)-1-METHYLPYRIDINIUM IODIDE 2-DI-1-ASP EINECS 218-460-8 1-METHYL-2-P-DIMETHYLAMINO-STYRYL-PYRIDINIUM-IODIDE |
| Description | 2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G-quadruplex (G4) structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-kit87up, c-myc)[1]. |
| References |
| Density | 1.091g/cm3 |
|---|---|
| Boiling Point | 397.8℃at 760 mmHg |
| Melting Point | 280ºC (dec.)(lit.) |
| Molecular Formula | C16H19IN2 |
| Molecular Weight | 366.24000 |
| Flash Point | 179.3℃ |
| Exact Mass | 366.05900 |
| PSA | 7.12000 |
| Vapour Pressure | 1.55E-06mmHg at 25°C |
| Index of Refraction | 1.668 |
| Water Solubility | DMSO: soluble |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |