| Name | 8-Bromo-2'-deoxyguanosine |
|---|---|
| Synonyms |
2'-Deoxy-8-bromoguanosine
C8-bromo-2'-deoxyguanosine Guanosine, 8-bromo-2'-deoxy- 8-Br-dG 8-bromo-2'-deoxyuanosine 8-Bromo-2'-deoxyguanosine 8-Bromo-2'-deoxy-D-guanosine 2-Amino-8-bromo-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one 8-bromo2'-deoxyguansine |
| Description | 8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 2.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 727ºC at 760 mmHg |
| Melting Point | >250ºC dec. |
| Molecular Formula | C10H12BrN5O4 |
| Molecular Weight | 346.14 |
| Flash Point | 393.5ºC |
| Exact Mass | 345.007263 |
| PSA | 139.28000 |
| LogP | -0.02 |
| Appearance | Powder | White to Off-white |
| Vapour Pressure | 3.46E-22mmHg at 25°C |
| Index of Refraction | 1.941 |
| Storage condition | -20°C Freezer |
| Water Solubility | Soluble in dimethyl sulfoxide, warm water and dimethyl formamide. |
| Hazard Codes | T+ |
|---|
|
~92%
13389-03-2 |
| Literature: Muenzel, Martin; Szeibert, Claudia; Glas, Andreas F.; Globisch, Daniel; Carell, Thomas Journal of the American Chemical Society, 2011 , vol. 133, # 14 p. 5186 - 5189 |
|
~39%
13389-03-2 |
| Literature: Gannett; Sura Synthetic Communications, 1993 , vol. 23, # 11 p. 1611 - 1615 |
|
~17%
13389-03-2 |
| Literature: Gannett; Sura Synthetic Communications, 1993 , vol. 23, # 11 p. 1611 - 1615 |