Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 8-Bromo-2'-deoxyguanosine
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Purity: 98.0%
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13389-03-2

13389-03-2 structure

Name: 8-Bromo-2'-deoxyguanosine
Chemical Name: 8-Bromo-2'-deoxyguanosine
CAS Number: 13389-03-2
Molecular Formula: C₁₀H₁₂BrN₅O₄
Molecular Weight: 346.14
Catalog: Biochemical Nucleoside drugs Deoxynucleotides and their analogues
Create Date: 2018-06-30 00:39:25
Modify Date: 2024-01-05 23:18:38
8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	8-Bromo-2'-deoxyguanosine
Synonyms	2'-Deoxy-8-bromoguanosine C8-bromo-2'-deoxyguanosine Guanosine, 8-bromo-2'-deoxy- 8-Br-dG 8-bromo-2'-deoxyuanosine 8-Bromo-2'-deoxyguanosine 8-Bromo-2'-deoxy-D-guanosine 2-Amino-8-bromo-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one 8-bromo2'-deoxyguansine

Description	8-Bromo-2'-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	2.5±0.1 g/cm3
Boiling Point	727ºC at 760 mmHg
Melting Point	>250ºC dec.
Molecular Formula	C₁₀H₁₂BrN₅O₄
Molecular Weight	346.14
Flash Point	393.5ºC
Exact Mass	345.007263
PSA	139.28000
LogP	-0.02
Appearance	Powder \| White to Off-white
Vapour Pressure	3.46E-22mmHg at 25°C
Index of Refraction	1.941
Storage condition	-20°C Freezer
Water Solubility	Soluble in dimethyl sulfoxide, warm water and dimethyl formamide.

Hazard Codes	T+

961-07-9

~92%

13389-03-2

Literature: Muenzel, Martin; Szeibert, Claudia; Glas, Andreas F.; Globisch, Daniel; Carell, Thomas Journal of the American Chemical Society, 2011 , vol. 133, # 14 p. 5186 - 5189

109460-89-1

~39%

13389-03-2

Literature: Gannett; Sura Synthetic Communications, 1993 , vol. 23, # 11 p. 1611 - 1615

69992-10-5

~17%

13389-03-2

Literature: Gannett; Sura Synthetic Communications, 1993 , vol. 23, # 11 p. 1611 - 1615

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