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Shanghai Jizhi Biochemical Technology Co., Ltd
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DC Chemicals Limited
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tyramine hydrochloride
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: Tyramine hydrochloride
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60-19-5

60-19-5 structure

60-19-5 structure

Name: Tyramine
Chemical Name: Tyramine hydrochloride
CAS Number: 60-19-5
Molecular Formula: C₈H₁₂ClNO
Molecular Weight: 137.179
Catalog: Research Areas Others
Create Date: 2018-10-01 18:59:19
Modify Date: 2024-01-02 20:50:50
Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods[1].

Name	Tyramine hydrochloride
Synonyms	p-b-Aminoethylphenol P-hydroxy-b-phenylethylamine Z2R DQ MFCD00012682 4-Hydroxy phenylethylamine EINECS 206-446-4 4-hydroxy-Benzeneethanamine Phenol, p- (2-aminoethyl)- 4-Hydroxy-β-phenylethylamine 4- (2-aminoethyl)-Phenol p-(2-aminoethyl)-Phenol α-(4-Hydroxyphenyl)-β-aminoethane β-(4-Hydroxyphenyl)ethylamine 2-p-Hydroxyphenylethylamine a-(4-Hydroxyphenyl)-b-aminoethane p-β-Aminoethylphenol 4-hydroxy-phenethylamine p-Hydroxy-β-phenethylamine 4-(2-Aminoethyl)phenol 4-(2-aminoethyl)phenol,hydrochloride b-(4-Hydroxyphenyl)ethylamine Phenol, 4-(2-aminoethyl)- P-hydroxy-β-phenylethylamine Tyramine base P-hydroxy-b-phenethylamine

Description	Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods[1].
Related Catalog	Research Areas >> Cardiovascular Disease
Target	Human Endogenous Metabolite
In Vitro	Tyramine is normally broken down in your body by an enzyme called MAO (monoamine oxidase)[1].
References	[1]. C Brown , et al. The Monoamine Oxidase Inhibitor-Tyramine Interaction. J Clin Pharmacol. 1989 Jun;29(6):529-32.

Density	1.1±0.1 g/cm3
Boiling Point	325.2±0.0 °C at 760 mmHg
Melting Point	253-255 °C(lit.)
Molecular Formula	C₈H₁₂ClNO
Molecular Weight	137.179
Flash Point	119.2±20.4 °C
Exact Mass	137.084061
PSA	46.25000
LogP	0.72
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.577
Storage condition	Store at RT.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SJ6050000

CHEMICAL NAME :: Phenol, p-(2-aminoethyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 60-19-5

LAST UPDATED :: 199709

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C8-H11-N-O.Cl-H

MOLECULAR WEIGHT :: 173.66

WISWESSER LINE NOTATION :: Z2R DQ &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 710 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 208 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1044 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 2530 umol/L

REFERENCE :: MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25-S36-S26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NL4375000
HS Code	29222900

Precursor 9
2982-55-0 14191-95-8 76457-44-8 68-12-2
99-93-4 74447-34-0 74447-35-1 66648-43-9
2982-54-9
DownStream 9
38961-21-6 501-94-0 20375-37-5 99-96-7
259263-97-3 95-50-1 626-00-6 624-38-4
1370640-86-0

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%