6001-64-5

6001-64-5 structure

Name: Chlorobutanol hemihydrate
Chemical Name: 1,1,1-Trichloro-2-Methyl-2-Propanol Hemihydrate
CAS Number: 6001-64-5
Molecular Formula: C₄H₉Cl₃O₂
Molecular Weight: 372.929
Catalog: analytical chemistry Standard Agricultural and environmental standards
Create Date: 2018-07-08 13:17:40
Modify Date: 2024-01-02 11:39:34
Chlorobutanol hemihydrate is a pharmaceutical preservative with sedative-hypnotic actions. Chlorobutanol hemihydrate is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol hemihydrate is widely used in food and cosmetic industry[1][2].

Name	1,1,1-Trichloro-2-Methyl-2-Propanol Hemihydrate
Synonyms	1,1,1-Trichloro-2-methyl-2-propanol hemihydrate 1,1,1-Trichloro-2-methyl-2-propanol hydrate (2:1) MFCD02179352 1,1,1-trichloro-2-methyl-2-propanol(hydrate) (2:1) Chlorobutanol Hemihydrate 1,1,1-Trichloro-2-methylpropan-2-ol hydrate (2:1) 2-Propanol, 1,1,1-trichloro-2-methyl-, hydrate (2:1)

Description	Chlorobutanol hemihydrate is a pharmaceutical preservative with sedative-hypnotic actions. Chlorobutanol hemihydrate is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol hemihydrate is widely used in food and cosmetic industry[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Neurological Disease Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Smoak IW, et al. Chlorobutanol: maternal serum levels and placental transfer in the mouse. Vet Hum Toxicol. 1997 Oct;39(5):287-90. [2]. Friesen WT, et al. The antibacterial stability of chlorobutanol stored in polyethylene bottles. Am J Hosp Pharm. 1971 Jul;28(7):507-12.

Boiling Point	167ºC
Melting Point	75-79ºC
Molecular Formula	C₄H₉Cl₃O₂
Molecular Weight	372.929
Flash Point	100ºC
Exact Mass	369.923065
PSA	29.46000
LogP	2.06320
Appearance	Crystalline Powder, Crystals and/or Chunks \| White to almost white
Storage condition	-20°C
Stability	Stable. Generates toxic fumes on combustion. Incompatible with strong oxidizing agents.
Water Solubility	Slightly soluble in water, very soluble in ethanol (96 per cent), soluble in glycerol (85 per cent). \| Soluble in ethanol, ether, chloroform, and glycerol. Insoluble in water.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	26-36/37/39
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UC0175000