74431-23-5
74431-23-5 structure
- Name: Imipenem
- Chemical Name: imipenem hydrate
- CAS Number: 74431-23-5
- Molecular Formula: C12H19N3O5S
- Molecular Weight: 317.36
- Catalog: API Antibiotics Beta-lactamase inhibitor
- Create Date: 2018-07-29 17:55:16
- Modify Date: 2026-06-30 16:26:32
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Imipenem monohydrate, a member of the carbapenem class of antibiotics isolated from the soil organism Streptomyces cattleya[1], is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including several multi-drug resistant bacterial species. Imipenem acts as cell wall-targeting antibiotic[2][3].
| Name | imipenem hydrate |
|---|---|
| Synonyms |
(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}thio)-7-oxo-1-azabicyclo[3.2.0]ht-2-ene-2-cboxylic acid monohydrate, Primaxin monohydrate, Tienam monohydrate
Imipenem monohydrate, >= 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, (5R,6S)-, hydrate (1:1) (6 R,7 R)-7-AMIMO-8-OXO-3-(1-PROPENYL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CBOXYLIC ACID Imipenem hydrate N-Formimidoylthienamycin Monohydrate Imipenem 1-hydrate Imipenem monohydrate Imipenem, Monohydrate Imipenem //BP (5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.]ht-2-ene-2-cboxylic acid hydrate Imipenem MonohydrateQ: What is Imipenem Monohydrate Q: What is the CAS Number of Imipenem Monohydrate Q: What is the storage condition of Imipenem Monohydrate mipenem monohydrate Crude Crude ade of Imipenem Imipenem Monohydrate, Antibiotic for Culture Media Use Only lmipemide EOS-61603 Imipenem crude(monohydrate non sterile) acide (5R,6S)-6-[(1R)-1-hydroxyéthyl]-3-({2-[(iminométhyl)amino]éthyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ène-2-carboxylique hydrate (6 R,7 R)-7-AMIMO-8-OXO-3-(1-PROPENYL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CBOXYLIC ACID Monohydrate MK-0787 (5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]ht-2-ene-2-cboxylic acid hydrate Imipenem Monohydrate (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate Imipenem Monohydrate (HPLC) (6 R ,7 R ) - 7-AMIMO-8-OXO-3-(1-PROPENYL)-5-THIA-1-AZABICYLO[4.2.0]OCT-2-ENE-2-CBOXYLIC ACID 5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CBOXYLIC ACID, 7-AMINO-8-OXO-3-(1-PROPENYL)-, (6R,7R) (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl) amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]ht-2-ene-2-cboxylic acid monohydrate (5R,6S)-3-((2-(Formimidoylamino)ethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid monohydrate (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-en-2-carbonsäurehydrat IMIPEMIDE MONOHYDRATE Imipenem（b） [5R-[5α，6α(R^<*>^)]]-6-(1-hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]ht-2-ene-2-cboxylic acid monohydrate (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-({2-[(iminomethyl)amino]ethyl}sulfanyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate (1:1) MFCD08458212 EINECS 264-734-5 lmipenem monohydrate (6R,7R)-7-AMIMO-8-OXO-3-(1-PROPENYL)-5-THIA-1-azabicyclo[4.2 Imipenem n-Hydrate 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-, (5R,6S)-, monohydrate Imipenem monohydrate (High purity) bacteria,Inhibitor,N-Formimidoyl thienamycin,P. aeruginosa,ntibiotic,MK0787,Imipenem monohydrate,MK 0787,MK-0787,infection,inhibit,Bacterial,Antibiotic,thienamycin Imipenem Monohydrate: (5R,6S)-6-[(R)-1-Hydroxyethyl]-3-[[2-[(iminomethyl)amino]ethyl]sulfanyl]-7-oxo-1-azabicyclo[3.2.0]ht-2-ene-2-cboxylic acid monohydrate [5R-[5a,6a(R*)]]-6-(1-Hydroxyethyl)-3-[[2-[(iminomethyl)amino]ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid Monohydrate Tienam monohydrate Primaxin monohydrate N-Formimidoyl thienamycin monohydrate |
| Description | Imipenem monohydrate, a member of the carbapenem class of antibiotics isolated from the soil organism Streptomyces cattleya[1], is an intravenous β-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria, including several multi-drug resistant bacterial species. Imipenem acts as cell wall-targeting antibiotic[2][3]. |
|---|---|
| Related Catalog | |
| References |
[2]. Jacoby GA, et al. AmpC beta-lactamases. Clin Microbiol Rev. 2009 Jan;22(1):161-82. |
| Density | 1.02 g/mL at 25 °C |
|---|---|
| Boiling Point | 34.6°C |
| Melting Point | -116.3°C |
| Molecular Formula | C12H19N3O5S |
| Molecular Weight | 317.36 |
| Flash Point | <−30 °F |
| Exact Mass | 317.104553 |
| PSA | 148.25000 |
| LogP | 0.18820 |
| Storage condition | -20°C Freezer |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | F+,C,F |
| Risk Phrases | R12:Extremely Flammable. R14/15:Reacts violently with water, liberating extremely flammable gases . R19:May form explosive peroxides. R22:Harmful if swallowed. R34:Causes burns. R66:Repeated exposure may cause skin dryness or cracking. R67:Vapors may cause |
| Safety Phrases | S16-S26-S36/37/39-S43-S45-S7/8-S27 |
| RIDADR | UN 3399 4.3/PG 1 |
| WGK Germany | 1 |
| Packaging Group | I |
| Hazard Class | 4.3 |