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Henan Tianfu Chemical Co., Ltd.
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12071-83-9

12071-83-9 structure

12071-83-9 structure

Name: propineb
Chemical Name: propineb
CAS Number: 12071-83-9
Molecular Formula: C₅H₈N₂S₄Zn
Molecular Weight: 289.77
Catalog: Chemical pesticide Fungicide Pesticide fungicide
Create Date: 2018-09-10 11:57:17
Modify Date: 2024-01-07 20:02:41
Propineb (Zinc propylenebis) is a compound widely used in fruit and vegetables cultures, due to its large spectrum of activity against fungal plant diseases[1].

Name	propineb
Synonyms	[[(1-Methyl-1,2-ethanediyl)bis[carbamodithioato]](2-)]zinc [Propylenebis(dithiocarbamato)]zinc ZINC TRIFLUOROACETATE trifluoro-acetic acid,zinc-trifluoroacetate EINECS 235-134-0 Zinc 1,2-propanediyldicarbamodithioate Zinc propane-1,2-diyldicarbamodithioate Carbamodithioic acid, N,N'-(1-methyl-1,2-ethanediyl)bis-, zinc salt (1:1) MFCD00055491 zinc rifluoroacetate zinc,N-[1-(sulfidocarbothioylamino)propan-2-yl]carbamodithioate

Description	Propineb (Zinc propylenebis) is a compound widely used in fruit and vegetables cultures, due to its large spectrum of activity against fungal plant diseases[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vivo	Propineb (Zinc propylenebis) has a moderate to low acute toxicity with a specific goitrogenic effect in rats. long-term exposure, oral or by inhalation is related to carcinogenicity, teratogenicity, malfunction of the reproductive system and malformation of their vitals[2].
References	[1]. Viviani B, et al. Dithiocarbamate propineb induces acetylcholine release through cytoskeletal actin depolymerization in PC12 cells. Toxicol Lett. 2008 Nov 10;182(1-3):63-8. [2]. Kazos EA, et al. Determination of dithiocarbamate fungicide propineb and its main metabolite propylenethiourea in airborne samples. Chemosphere. 2007 Aug;68(11):2104-10.

Boiling Point	315.4ºC at 760 mmHg
Melting Point	160ºC
Molecular Formula	C₅H₈N₂S₄Zn
Molecular Weight	289.77
Flash Point	144.5ºC
Exact Mass	287.886169
PSA	165.84000
LogP	1.76530

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZH4950000

CHEMICAL NAME :: Zinc, (N,N'-propylene-1,2-bis(dithiocarbamate))

CAS REGISTRY NUMBER :: 12071-83-9

LAST UPDATED :: 199409

DATA ITEMS CITED :: 12

WISWESSER LINE NOTATION :: SUYS&MY1&1MYS&US &ZN-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >693 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2300 mg/kg

SEX/DURATION :: female 11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2300 mg/kg

SEX/DURATION :: female 11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - homeostasis

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 1 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 2 gm/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 2600 mg/kg/5D (Intermittent)

REFERENCE :: PRKHDK Problemi na Khigienata. Problems in Hygiene. (Durzhavno Izdatel'stvo Meditsina i Fizkultura, Pl. Slaveikov 11, Sofia, Bulgaria) V.1- 1975- Volume(issue)/page/year: 4,151,1979

Personal Protective Equipment	Eyeshields;Faceshields;Gloves
Hazard Codes	N: Dangerous for the environment;
Risk Phrases	51/53
Safety Phrases	60-61
RIDADR	UN3077 9/PG 3
RTECS	ZH4950000
Packaging Group	III
HS Code	2930200012

HS Code	2930200012
Summary	2930200012 iron(iii) dimethylcarbamodithioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%