12071-83-9

• 常用中文名：丙森锌
• 常用英文名：propineb
• CAS号：12071-83-9
• 分子式：C₅H₈N₂S₄Zn
• 分子量：289.77
• 相关类别： 化学农药原药 杀菌剂 农药杀菌剂
• 发布时间：2018-09-10 11:57:17
• 更新时间：2026-07-01 18:34:05
• Propineb (Zinc propylenebis) 是一种广泛用于水果和蔬菜病害的化合物,其具有抗植物真菌疾病的广谱活性。

名称

• 中文名: 丙森锌
• 英文名: propineb
• 中文别名: 甲基锌乃浦; 丙森锌(工业级); 乙腈:二甲基亚砜=4:1中丙森锌/GB26; 丙森锌/GB 26; 丙森锌,10 MM DMSO 溶液; 甲代森锌 标准品; 甲代森锌(丙森锌) 标准品; 丙森锌标准品; 丙森锌符合GB27632016; 丙森锌Propineb; 丙烯基双二硫代氨基甲酸锌
• 英文别名: propinebe; AOCOL(R); ZINROPYLENEBISTHIOCBAMATE; taifen; KORUNEB; [[(1-METHYL-1,2-ETHANEDIYL)BIS[CBAMO-DITHIOATO]](2-)]ZINC HOMOPOLYMER; AOCOL; zinc rifluoroacetate; Propineb Standd; PROPINEB; MEZINEB; ENERCOL; bay46131; [Propylenebis(dithiocarbamato)]zinc; trifluoro-acetic acid,zinc-trifluoroacetate; zink-(n,n’-propylen-1,2-bis(dithiocbamat)); propylenebis(dithiocbamato)zinc; Zinc 1,2-propanediyldicarbamodithioate; Methylzineb; lh30/z; ANTRACOL(R); Zinc propane-1,2-diyldicarbamodithioate; MFCD00055491; PROPINEB MIXTURE, PESTANAL; [2-(Sulfidocbothioylamino)propylamino]methanedithioate zinc(+2) cation; airone; Propineb ( ade); ANTRACOL; Propineb, 10 mM in DMSO; PropinebSolution,1000mg/L; polymeric zinc propylenebis(dithiocbamate); lh3012; ZINC TRIFLUOROACETATE; Vortioxetine Impurity 94; Antracol70; bayer46131; Carbamodithioic acid, N,N'-(1-methyl-1,2-ethanediyl)bis-, zinc salt (1:1); [[(1-Methyl-1,2-ethanediyl)bis[cbamodithioate](2-)]]zinc; tsipromat; AIRONE(R); C16490000 Propineb; [[(1-Methyl-1,2-ethanediyl)bis[carbamodithioato]](2-)]zinc; EINECS 235-134-0; propineb (bsi,iso,jmaf); (1-methyl-1,2-ethanediyl)bis-cbamodithioic acid zinc complex; zinc,N-[1-(sulfidocarbothioylamino)propan-2-yl]carbamodithioate

物化性质

• 沸点: 315.4ºC at 760 mmHg
• 熔点: 160ºC
• 分子式: C₅H₈N₂S₄Zn
• 分子量: 289.77
• 闪点: 144.5ºC
• 精确质量: 287.886169
• PSA: 165.84000
• LogP: 1.76530
• 外观性状: 白色或淡黄色粉末
• 储存条件: 库房通风低温干燥,与食品原料分开储运
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:2

  3.氢键受体数量:4

  4.可旋转化学键数量:3

  5.互变异构体数量:4

  6.拓扑分子极性表面积:90.2

  7.重原子数量:12

  8.表面电荷:0

  9.复杂度:148

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:1

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

生物活性

• 描述: Propineb (Zinc propylenebis) 是一种广泛用于水果和蔬菜病害的化合物,其具有抗植物真菌疾病的广谱活性。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 体内研究: Propineb(Zrate propylenebis)具有中等至低的急性毒性,在大鼠中具有特定的致甲状腺肿毒作用。长期接触,口服或吸入与致癌性,致畸性,生殖系统功能失常和生命体质畸形有关[2]。
• 参考文献:

  [1]. Viviani B, et al. Dithiocarbamate propineb induces acetylcholine release through cytoskeletal actin depolymerization in PC12 cells. Toxicol Lett. 2008 Nov 10;182(1-3):63-8.

  [2]. Kazos EA, et al. Determination of dithiocarbamate fungicide propineb and its main metabolite propylenethiourea in airborne samples. Chemosphere. 2007 Aug;68(11):2104-10.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : ZH4950000 CHEMICAL NAME : Zinc, (N,N'-propylene-1,2-bis(dithiocarbamate)) CAS REGISTRY NUMBER : 12071-83-9 LAST UPDATED : 199409 DATA ITEMS CITED : 12 WISWESSER LINE NOTATION : SUYS&MY1&1MYS&US &ZN- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 8500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >693 mg/m3/4H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Bird - quail DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 2300 mg/kg SEX/DURATION : female 11 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 2300 mg/kg SEX/DURATION : female 11 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - homeostasis TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 1 gm/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - other developmental abnormalities TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 2 gm/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) MUTATION DATA TEST SYSTEM : Rodent - rat DOSE/DURATION : 2600 mg/kg/5D (Intermittent) REFERENCE : PRKHDK Problemi na Khigienata. Problems in Hygiene. (Durzhavno Izdatel'stvo Meditsina i Fizkultura, Pl. Slaveikov 11, Sofia, Bulgaria) V.1- 1975- Volume(issue)/page/year: 4,151,1979

安全

• 个人防护装备: Eyeshields;Faceshields;Gloves
• 危害码 (欧洲): N: Dangerous for the environment;
• 风险声明 (欧洲): 51/53
• 安全声明 (欧洲): 60-61
• 危险品运输编码: UN3077 9/PG 3
• RTECS号: ZH4950000
• 包装等级: III
• 海关编码: 2930200012

海关

海关编码	2930200012
中文概述	2930200012 威百亩、代森钠、丙森锌、福美铁等〔包括福美锌、代森福美锌、安百亩〕。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
监管条件	S.进出口农药登记证明
Summary	2930200012 iron(iii) dimethylcarbamodithioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%